LRCH4_HUMAN » Leucine-rich repeat and calponin homology domain-containing protein 4

LRCH4_HUMAN » Leucine-rich repeat and calponin homology domain-containing protein 4
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Topology in Membrane
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LRCH4_HUMAN » Leucine-rich repeat and calponin homology domain-containing protein 4 » Leucine-rich repeat neuronal protein 4;Leucine-rich neuronal protein;
Hydrophobic Thickness 30.8 ± 2.8 Å
Tilt Angle 9 ± 6°
ΔGtransfer -22.5 kcal/mol
ΔGfold -15.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Und
TM Segments 658-678 (656-681)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 68-126, PDBID: 4LI1, Subunit A, Seq Identity:38%, Leucine rich repeat

AA: 137-194, PDBID: 2Z81, Subunit A, Seq Identity:41%, Leucine rich repeat

AA: 535-641, PDBID: 2L3G, Subunit A, Seq Identity:27%, Calponin homology (CH) domain

UniProt features for LRCH4_HUMAN » Leucine-rich repeat and calponin homology domain-containing protein 4
CHAIN 1 683 Leucine-rich repeat and calponin homology domain-containing protein 4.

REPEAT 43 64 LRR 1.

REPEAT 69 90 LRR 2.

REPEAT 92 114 LRR 3.

REPEAT 115 136 LRR 4.

REPEAT 137 158 LRR 5.

REPEAT 160 182 LRR 6.

REPEAT 183 205 LRR 7.

REPEAT 206 226 LRR 8.

REPEAT 228 249 LRR 9.

DOMAIN 534 649 CH.

Amino Acid Sequence for LRCH4_HUMAN » Leucine-rich repeat and calponin homology domain-containing protein 4
MAAAVAAPLA AGGEEAAATT SVPGSPGLPG RRSAERALEE AVATGTLNLS NRRLKHFPRG AARSYDLSDI TQADLSRNRF PEVPEAACQL VSLEGLSLYH NCLRCLNPAL GNLTALTYLN LSRNQLSLLP PYICQLPLRV LIVSNNKLGA LPPDIGTLGS LRQLDVSSNE LQSLPSELCG LSSLRDLNVR RNQLSTLPEE LGDLPLVRLD FSCNRVSRIP VSFCRLRHLQ VILLDSNPLQ SPPAQVCLKG KLHIFKYLST EAGQRGSALG DLAPSRPPSF SPCPAEDLFP GHRYDGGLDS GFHSVDSGSK RWSGNESTDE FSELSFRISE LAREPRGPRE RKEDGSADGD PVQIDFIDSH VPGEDEERGT VEEQRPPELS PGAGDRERAP SSRREEPAGE ERRRPDTLQL WQERERRQQQ QSGAWGAPRK DSLLKPGLRA VVGGAAAVST QAMHNGSPKS SASQAGAAAG QGAPAPAPAS QEPLPIAGPA TAPAPRPLGS IQRPNSFLFR SSSQSGSGPS SPDSVLRPRR YPQVPDEKDL MTQLRQVLES RLQRPLPEDL AEALASGVIL CQLANQLRPR SVPFIHVPSP AVPKLSALKA RKNVESFLEA CRKMGVPEAD LCSPSDLLQG TARGLRTALE AVKRVGGKAL PPLWPPSGLG GFVVFYVVLM LLLYVTYTRL LGS