LRC15_HUMAN » Leucine-rich repeat-containing protein 15

LRC15_HUMAN » Leucine-rich repeat-containing protein 15
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
LRC15_HUMAN » Leucine-rich repeat-containing protein 15 » Leucine-rich repeat protein induced by beta-amyloid homolog;hLib;
Hydrophobic Thickness 30.8 ± 3.4 Å
Tilt Angle 0 ± 11°
ΔGtransfer -17.6 kcal/mol
ΔGfold -17.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 536-556 (534-567)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 149-209, PDBID: 4BV4, Subunit R, Seq Identity:46%, Leucine rich repeat

AA: 197-257, PDBID: 4BSR, Subunit B, Seq Identity:45%, Leucine rich repeat

AA: 245-305, PDBID: 4P8S, Subunit A, Seq Identity:44%, Leucine rich repeat

AA: 293-353, PDBID: 4KT1, Subunit A, Seq Identity:46%, Leucine rich repeat

AA: 365-424, PDBID: 4P8S, Subunit A, Seq Identity:39%, Leucine rich repeat

UniProt annotation for LRC15_HUMAN » Leucine-rich repeat-containing protein 15
TISSUE SPECIFICITY: Brain and placenta.
UniProt features for LRC15_HUMAN » Leucine-rich repeat-containing protein 15
SIGNAL 1 21 Potential.
CHAIN 22 581 Leucine-rich repeat-containing protein 15.
DOMAIN 22 53 LRRNT.
REPEAT 54 75 LRR 1.
REPEAT 78 99 LRR 2.
REPEAT 102 123 LRR 3.
REPEAT 126 147 LRR 4.
REPEAT 150 171 LRR 5.
REPEAT 174 195 LRR 6.
REPEAT 198 219 LRR 7.
REPEAT 222 243 LRR 8.
REPEAT 246 267 LRR 9.
REPEAT 270 291 LRR 10.
REPEAT 294 315 LRR 11.
REPEAT 318 339 LRR 12.
REPEAT 342 363 LRR 13.
REPEAT 366 387 LRR 14.
REPEAT 390 411 LRR 15.
DOMAIN 423 475 LRRCT.
Amino Acid Sequence for LRC15_HUMAN » Leucine-rich repeat-containing protein 15
MPLKHYLLLL VGCQAWGAGL AYHGCPSECT CSRASQVECT GARIVAVPTP LPWNAMSLQI LNTHITELNE SPFLNISALI ALRIEKNELS RITPGAFRNL GSLRYLSLAN NKLQVLPIGL FQGLDSLESL LLSSNQLLQI QPAHFSQCSN LKELQLHGNH LEYIPDGAFD HLVGLTKLNL GKNSLTHISP RVFQHLGNLQ VLRLYENRLT DIPMGTFDGL VNLQELALQQ NQIGLLSPGL FHNNHNLQRL YLSNNHISQL PPSIFMQLPQ LNRLTLFGNS LKELSLGIFG PMPNLRELWL YDNHISSLPD NVFSNLRQLQ VLILSRNQIS FISPGAFNGL TELRELSLHT NALQDLDGNV FRMLANLQNI SLQNNRLRQL PGNIFANVNG LMAIQLQNNQ LENLPLGIFD HLGKLCELRL YDNPWRCDSD ILPLRNWLLL NQPRLGTDTV PVCFSPANVR GQSLIIINVN VAVPSVHVPE VPSYPETPWY PDTPSYPDTT SVSSTTELTS PVEDYTDLTT IQVTDDRSVW GMTQAQSGLA IAAIVIGIVA LACSLAACVG CCCCKKRSQA VLMQMKAPNE C