LMTK3_HUMAN » Serine/threonine-protein kinase LMTK3

LMTK3_HUMAN » Serine/threonine-protein kinase LMTK3
Magnify LMTK3_HUMAN » Serine/threonine-protein kinase LMTK3Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Endosome membrane
Topologyendosome lumenal side
cytoplasmic side
LMTK3_HUMAN » Serine/threonine-protein kinase LMTK3 » Lemur tyrosine kinase 3;
Hydrophobic Thickness 32.8 ± 2.8 Å
Tilt Angle 0 ± 1°
ΔGtransfer -33.4 kcal/mol
ΔGfold -16.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 41-61 (38-64)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 133-408, PDBID: 1YVJ, Subunit A, Seq Identity:41%, Protein tyrosine kinase

UniProt annotation for LMTK3_HUMAN » Serine/threonine-protein kinase LMTK3
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
UniProt features for LMTK3_HUMAN » Serine/threonine-protein kinase LMTK3
SIGNAL 1 20 Potential.
CHAIN 21 1460 Serine/threonine-protein kinase LMTK3.
DOMAIN 133 411 Protein kinase.
ACT_SITE 266 266 Proton acceptor (By similarity).
Amino Acid Sequence for LMTK3_HUMAN » Serine/threonine-protein kinase LMTK3
MPAPGALILL AAVSASGCLA SPAHPDGFAL GRAPLAPPYA VVLISCSGLL AFIFLLLTCL CCKRGDVGFK EFENPEGEDC SGEYTPPAEE TSSSQSLPDV YILPLAEVSL PMPAPQPSHS DMTTPLGLSR QHLSYLQEIG SGWFGKVILG EIFSDYTPAQ VVVKELRASA GPLEQRKFIS EAQPYRSLQH PNVLQCLGLC VETLPFLLIM EFCQLGDLKR YLRAQRPPEG LSPELPPRDL RTLQRMGLEI ARGLAHLHSH NYVHSDLALR NCLLTSDLTV RIGDYGLAHS NYKEDYYLTP ERLWIPLRWA APELLGELHG TFMVVDQSRE SNIWSLGVTL WELFEFGAQP YRHLSDEEVL AFVVRQQHVK LARPRLKLPY ADYWYDILQS CWRPPAQRPS ASDLQLQLTY LLSERPPRPP PPPPPPRDGP FPWPWPPAHS APRPGTLSSP FPLLDGFPGA DPDDVLTVTE SSRGLNLECL WEKARRGAGR GGGAPAWQPA SAPPAPHANP SNPFYEALST PSVLPVISAR SPSVSSEYYI RLEEHGSPPE PLFPNDWDPL DPGVPAPQAP QAPSEVPQLV SETWASPLFP APRPFPAQSS ASGSFLLSGW DPEGRGAGET LAGDPAEVLG ERGTAPWVEE EEEEEEGSSP GEDSSSLGGG PSRRGPLPCP LCSREGACSC LPLERGDAVA GWGGHPALGC PHPPEDDSSL RAERGSLADL PMAPPASAPP EFLDPLMGAA APQYPGRGPP PAPPPPPPPP RAPADPAASP DPPSAVASPG SGLSSPGPKP GDSGYETETP FSPEGAFPGG GAAEEEGVPR PRAPPEPPDP GAPRPPPDPG PLPLPGPREK PTFVVQVSTE QLLMSLREDV TRNLLGEKGA TARETGPRKA GRGPGNREKV PGLNRDPTVL GNGKQAPSLS LPVNGVTVLE NGDQRAPGIE EKAAENGALG SPEREEKVLE NGELTPPRRE EKALENGELR SPEAGEKVLV NGGLTPPKSE DKVSENGGLR FPRNTERPPE TGPWRAPGPW EKTPESWGPA PTIGEPAPET SLERAPAPSA VVSSRNGGET APGPLGPAPK NGTLEPGTER RAPETGGAPR APGAGRLDLG SGGRAPVGTG TAPGGGPGSG VDAKAGWVDN TRPQPPPPPL PPPPEAQPRR LEPAPPRARP EVAPEGEPGA PDSRAGGDTA LSGDGDPPKP ERKGPEMPRL FLDLGPPQGN SEQIKARLSR LSLALPPLTL TPFPGPGPRR PPWEGADAGA AGGEAGGAGA PGPAEEDGED EDEDEEEDEE AAAPGAAAGP RGPGRARAAP VPVVVSSADA DAARPLRGLL KSPRGADEPE DSELERKRKM VSFHGDVTVY LFDQETPTNE LSVQAPPEGD TDPSTPPAPP TPPHPATPGD GFPSNDSGFG GSFEWAEDFP LLPPPGPPLC FSRFSVSPAL ETPGPPARAP DARPAGPVEN