|LIRA5_HUMAN » Leukocyte immunoglobulin-like receptor subfamily A member 5 » CD85 antigen-like family member F;Immunoglobulin-like transcript 11;ILT-11; Leukocyte immunoglobulin-like receptor 9;LIR-9;|
|Hydrophobic Thickness||29.2 ± 1.6 Å|
|Tilt Angle||0 ± 0°|
|Links||UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC|
|TM Segments||262-287 (262-292)|
Osteoclast differentiation (KEGG)
|UniProt annotation for LIRA5_HUMAN » Leukocyte immunoglobulin-like receptor subfamily A member 5|
|FUNCTION: May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition. TISSUE SPECIFICITY: Expressed mostly in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Among leukocytes, monocytes and neutrophils express the highest level. Expressed in CD14+ monocytes, but not in T-cells, B-cells or natural killer (NK) cells (at protein level).|
|UniProt features for LIRA5_HUMAN » Leukocyte immunoglobulin-like receptor subfamily A member 5|
SIGNAL 1 41 Potential. |
CHAIN 42 299 Leukocyte immunoglobulin-like receptor subfamily A member 5.
DOMAIN 51 136 Ig-like C2-type 1.
DOMAIN 142 230 Ig-like C2-type 2.
DISULFID 67 116 By similarity.
DISULFID 162 214 By similarity.
|Amino Acid Sequence for LIRA5_HUMAN » Leukocyte immunoglobulin-like receptor subfamily A member 5|
|MAPWSHPSAQ LQPVGGDAVS PALMVLLCLG LSLGPRTHVQ AGNLSKATLW AEPGSVISRG NSVTIRCQGT LEAQEYRLVK EGSPEPWDTQ NPLEPKNKAR FSIPSMTEHH AGRYRCYYYS PAGWSEPSDP LELVVTGFYN KPTLSALPSP VVTSGENVTL QCGSRLRFDR FILTEEGDHK LSWTLDSQLT PSGQFQALFP VGPVTPSHRW MLRCYGSRRH ILQVWSEPSD LLEIPVSGAA DNLSPSQNKS DSGTASHLQD YAVENLIRMG MAGLILVVLG ILIFQDWHSQ RSPQAAAGR|