LIGO4_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4

LIGO4_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
LIGO4_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4 » Leucine-rich repeat neuronal protein 6D;
Hydrophobic Thickness 33.2 ± 5.6 Å
Tilt Angle 39 ± 0°
ΔGtransfer -25.3 kcal/mol
ΔGfold -16.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 527-556 (527-561)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 62-120, PDBID: 3WPE, Subunit A, Seq Identity:49%, Leucine rich repeat

AA: 112-168, PDBID: 2ID5, Subunit D, Seq Identity:52%, Leucine rich repeat

AA: 156-216, PDBID: 4P8S, Subunit A, Seq Identity:44%, Leucine rich repeat

AA: 253-312, PDBID: 4Z0C, Subunit D, Seq Identity:39%, Leucine rich repeat

AA: 310-360, PDBID: 3J0A, Subunit A, Seq Identity:42%, Leucine rich repeat

AA: 416-501, PDBID: 1NCT, Subunit A, Seq Identity:37%, Immunoglobulin I-set domain

UniProt features for LIGO4_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4
SIGNAL 1 28 Potential.
CHAIN 29 593 Leucine-rich repeat and immunoglobulin- like domain-containing nogo receptor- interacting protein 4.
DOMAIN 29 60 LRRNT.
REPEAT 61 82 LRR 1.
REPEAT 85 106 LRR 2.
REPEAT 109 130 LRR 3.
REPEAT 133 154 LRR 4.
REPEAT 157 178 LRR 5.
REPEAT 181 202 LRR 6.
REPEAT 210 231 LRR 7.
REPEAT 253 274 LRR 8.
REPEAT 277 298 LRR 9.
REPEAT 301 322 LRR 10.
REPEAT 325 346 LRR 11.
DOMAIN 358 412 LRRCT.
DOMAIN 412 502 Ig-like C2-type.
DISULFID 435 484 By similarity.
Amino Acid Sequence for LIGO4_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4
MDAATAPKQA WPPWPPLLFL LLLPGGSGGS CPAVCDCTSQ PQAVLCGHRQ LEAVPGGLPL DTELLDLSGN RLWGLQQGML SRLSLLQELD LSYNQLSTLE PGAFHGLQSL LTLRLQGNRL RIMGPGVFSG LSALTLLDLR LNQIVLFLDG AFGELGSLQK LEVGDNHLVF VAPGAFAGLA KLSTLTLERC NLSTVPGLAL ARLPALVALR LRELDIGRLP AGALRGLGQL KELEIHLWPS LEALDPGSLV GLNLSSLAIT RCNLSSVPFQ ALYHLSFLRV LDLSQNPISA IPARRLSPLV RLQELRLSGA CLTSIAAHAF HGLTAFHLLD VADNALQTLE ETAFPSPDKL VTLRLSGNPL TCDCRLLWLL RLRRHLDFGM SPPACAGPHH VQGKSLKEFS DILPPGHFTC KPALIRKSGP RWVIAEEGGH AVFSCSGDGD PAPTVSWMRP HGAWLGRAGR VRVLEDGTLE IRSVQLRDRG AYVCVVSNVA GNDSLRTWLE VIQVEPPNGT LSDPNITVPG IPGPFFLDSR GVAMVLAVGF LPFLTSVTLC FGLIALWSKG KGRVKHHMTF DFVAPRPSGD KNSGGNRVTA KLF