LIGO3_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3

LIGO3_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
LIGO3_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 » Leucine-rich repeat neuronal protein 2;Leucine-rich repeat neuronal protein 6B;
Hydrophobic Thickness 39.2 ± 0.8 Å
Tilt Angle 0 ± 0°
ΔGtransfer -66.8 kcal/mol
ΔGfold -21.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 524-553 (524-556)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 44-90, PDBID: 3REZ, Subunit B, Seq Identity:56%, Leucine rich repeat

AA: 54-114, PDBID: 2ID5, Subunit D, Seq Identity:60%, Leucine rich repeat

AA: 102-162, PDBID: 2ID5, Subunit D, Seq Identity:71%, Leucine rich repeat

AA: 152-210, PDBID: 1OZN, Subunit A, Seq Identity:40%, Leucine rich repeat

AA: 246-306, PDBID: 4Z0C, Subunit D, Seq Identity:42%, Leucine rich repeat

AA: 299-354, PDBID: 2ID5, Subunit D, Seq Identity:59%, Leucine rich repeat

AA: 406-484, PDBID: 4X8X, Subunit B, Seq Identity:31%, Immunoglobulin domain

UniProt features for LIGO3_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3
SIGNAL 1 24 Potential.
CHAIN 25 592 Leucine-rich repeat and immunoglobulin- like domain-containing nogo receptor- interacting protein 3.
DOMAIN 25 54 LRRNT.
REPEAT 55 76 LRR 1.
REPEAT 79 100 LRR 2.
REPEAT 103 124 LRR 3.
REPEAT 127 148 LRR 4.
REPEAT 151 172 LRR 5.
REPEAT 175 196 LRR 6.
REPEAT 207 228 LRR 7.
REPEAT 247 268 LRR 8.
REPEAT 271 292 LRR 9.
REPEAT 295 316 LRR 10.
REPEAT 319 340 LRR 11.
DOMAIN 352 406 LRRCT.
DOMAIN 407 496 Ig-like C2-type.
DISULFID 429 480 By similarity.
Amino Acid Sequence for LIGO3_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3
MTCWLCVLSL PLLLLPAAPP PAGGCPARCE CTVQTRAVAC TRRRLTAVPD GIPAETRLLE LSRNRIRCLN PGDLAALPAL EELDLSENAI AHVEPGAFAN LPRLRVLRLR GNQLKLIPPG VFTRLDNLTL LDLSENKLVI LLDYTFQDLH SLRRLEVGDN DLVFVSRRAF AGLLALEELT LERCNLTALS GESLGHLRSL GALRLRHLAI ASLEDQNFRR LPGLLHLEID NWPLLEEVAA GSLRGLNLTS LSVTHTNITA VPAAALRHQA HLTCLNLSHN PISTVPRGSF RDLVRLRELH LAGALLAVVE PQAFLGLRQI RLLNLSNNLL STLEESTFHS VNTLETLRVD GNPLACDCRL LWIVQRRKTL NFDGRLPACA TPAEVRGDAL RNLPDSVLFE YFVCRKPKIR ERRLQRVTAT AGEDVRFLCR AEGEPAPTVA WVTPQHRPVT ATSAGRARVL PGGTLEIQDA RPQDSGTYTC VASNAGGNDT YFATLTVRPE PAANRTPGEA HNETLAALRA PLDLTTILVS TAMGCITFLG VVLFCFVLLF VWSRGRGQHK NNFSVEYSFR KVDGPAAAAG QGGARKFNMK MI