LIGO2_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2

LIGO2_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2
Magnify LIGO2_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2Enlarged view of image
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
LIGO2_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 » Leucine-rich repeat neuronal protein 3;Leucine-rich repeat neuronal protein 6C;
Hydrophobic Thickness 39.6 ± 1.0 Å
Tilt Angle 0 ± 0°
ΔGtransfer -65.3 kcal/mol
ΔGfold -21.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 538-569 (538-570)
Pathways none
PDB none
OPM none
Complexes none
Interactions

A4, Complex: A4:LIGO2, PubMed

Domains

AA: 81-141, PDBID: 2ID5, Subunit D, Seq Identity:76%, Leucine rich repeat

AA: 105-165, PDBID: 2ID5, Subunit D, Seq Identity:90%, Leucine rich repeat

AA: 129-189, PDBID: 2ID5, Subunit C, Seq Identity:96%, Leucine rich repeat

AA: 250-309, PDBID: 4Z0C, Subunit D, Seq Identity:39%, Leucine rich repeat

AA: 297-357, PDBID: 2ID5, Subunit D, Seq Identity:58%, Leucine rich repeat

AA: 410-500, PDBID: 2ID5, Subunit D, Seq Identity:59%, Immunoglobulin I-set domain

UniProt features for LIGO2_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2
SIGNAL 1 27 Potential.
CHAIN 28 606 Leucine-rich repeat and immunoglobulin- like domain-containing nogo receptor- interacting protein 2.
DOMAIN 28 57 LRRNT.
REPEAT 58 79 LRR 1.
REPEAT 82 103 LRR 2.
REPEAT 106 127 LRR 3.
REPEAT 130 151 LRR 4.
REPEAT 154 175 LRR 5.
REPEAT 178 199 LRR 6.
REPEAT 202 223 LRR 7.
REPEAT 226 247 LRR 8.
REPEAT 250 271 LRR 9.
REPEAT 274 295 LRR 10.
REPEAT 298 319 LRR 11.
REPEAT 322 343 LRR 12.
DOMAIN 355 409 LRRCT.
DOMAIN 410 499 Ig-like C2-type.
DISULFID 432 483 By similarity.
Amino Acid Sequence for LIGO2_HUMAN » Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2
MLHTAISCWQ PFLGLAVVLI FMGSTIGCPA RCECSAQNKS VSCHRRRLIA IPEGIPIETK ILDLSKNRLK SVNPEEFISY PLLEEIDLSD NIIANVEPGA FNNLFNLRSL RLKGNRLKLV PLGVFTGLSN LTKLDISENK IVILLDYMFQ DLHNLKSLEV GDNDLVYISH RAFSGLLSLE QLTLEKCNLT AVPTEALSHL RSLISLHLKH LNINNMPVYA FKRLFHLKHL EIDYWPLLDM MPANSLYGLN LTSLSVTNTN LSTVPFLAFK HLVYLTHLNL SYNPISTIEA GMFSDLIRLQ ELHIVGAQLR TIEPHSFQGL RFLRVLNVSQ NLLETLEENV FSSPRALEVL SINNNPLACD CRLLWILQRQ PTLQFGGQQP MCAGPDTIRE RSFKDFHSTA LSFYFTCKKP KIREKKLQHL LVDEGQTVQL ECSADGDPQP VISWVTPRRR FITTKSNGRA TVLGDGTLEI RFAQDQDSGM YVCIASNAAG NDTFTASLTV KGFASDRFLY ANRTPMYMTD SNDTISNGTN ANTFSLDLKT ILVSTAMGCF TFLGVVLFCF LLLFVWSRGK GKHKNSIDLE YVPRKNNGAV VEGEVAGPRR FNMKMI