LEMD1_HUMAN » LEM domain-containing protein 1

LEMD1_HUMAN » LEM domain-containing protein 1
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Topology in Nuclear inner membrane
Topologyintermembrane space
nucleus matrix side
LEMD1_HUMAN » LEM domain-containing protein 1 » Cancer/testis antigen 50;CT50; LEM domain protein 1;LEMP-1;
Hydrophobic Thickness 32.4 ± 2.8 Å
Tilt Angle 15 ± 3°
ΔGtransfer -26.6 kcal/mol
ΔGfold -17.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 153-174 (153-177)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 3-42, PDBID: 1GJJ, Subunit A, Seq Identity:56%, LEM domain

UniProt annotation for LEMD1_HUMAN » LEM domain-containing protein 1
TISSUE SPECIFICITY: Testis-specific. Isoform 6 is detected in 17 of 18 colon cancer tissues examined.
UniProt features for LEMD1_HUMAN » LEM domain-containing protein 1
CHAIN 1 181 LEM domain-containing protein 1.
DOMAIN 1 45 LEM.
Amino Acid Sequence for LEMD1_HUMAN » LEM domain-containing protein 1
MVDVKCLSDC KLQNQLEKLG FSPGPILPST RKLYEKKLVQ LLVSPPCAPP VMNGPRELDG AQDSDDSEEL NIILQGNIIL STEKSKKLKK WPEASTTKRK AVDTYCLDYK PSKGRRWAAR APSTRITYGT ITKERDYCAE DQTIESWREE GFPVGLKLAV LGIFIIVVFV YLTVENKSLF G