LACS8_ARATH » Long chain acyl-CoA synthetase 8

LACS8_ARATH » Long chain acyl-CoA synthetase 8
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Topology in Membrane
Topologyouter side
inner side
LACS8_ARATH » Long chain acyl-CoA synthetase 8 »
Hydrophobic Thickness 30.4 ± 2.4 Å
Tilt Angle 29 ± 0°
ΔGtransfer -17.2 kcal/mol
ΔGfold -10.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Und
TM Segments 20-44 (20-50)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 107-588, PDBID: 4FUQ, Subunit A, Seq Identity:27%, AMP-binding enzyme

UniProt annotation for LACS8_ARATH » Long chain acyl-CoA synthetase 8
FUNCTION: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate.
UniProt features for LACS8_ARATH » Long chain acyl-CoA synthetase 8
CHAIN 1 720 Long chain acyl-CoA synthetase 8.

REGION 554 582 Fatty acid-binding.

Amino Acid Sequence for LACS8_ARATH » Long chain acyl-CoA synthetase 8
MEDSGVNPMD SPSKGSDFGV YGIIGGGIVA LLVPVLLSVV LNGTKKGKKR GVPIKVGGEE GYTMRHARAP ELVDVPWEGA ATMPALFEQS CKKYSKDRLL GTREFIDKEF ITASDGRKFE KLHLGEYKWQ SYGEVFERVC NFASGLVNVG HNVDDRVAIF SDTRAEWFIA FQGCFRQSIT VVTIYASLGE EALIYSLNET RVSTLICDSK QLKKLSAIQS SLKTVKNIIY IEEDGVDVAS SDVNSMGDIT VSSISEVEKL GQKNAVQPIL PSKNGVAVIM FTSGSTGLPK GVMITHGNLV ATAAGVMKVV PKLDKNDTYI AYLPLAHVFE LEAEIVVFTS GSAIGYGSAM TLTDTSNKVK KGTKGDVSAL KPTIMTAVPA ILDRVREGVL KKVEEKGGMA KTLFDFAYKR RLAAVDGSWF GAWGLEKMLW DALVFKKIRA VLGGHIRFML VGGAPLSPDS QRFINICMGS PIGQGYGLTE TCAGATFSEW DDPAVGRVGP PLPCGYVKLV SWEEGGYRIS DKPMPRGEIV VGGNSVTAGY FNNQEKTDEV YKVDEKGTRW FYTGDIGRFH PDGCLEVIDR KKDIVKLQHG EYVSLGKVEA ALGSSNYVDN IMVHADPINS YCVALVVPSR GALEKWAEEA GVKHSEFAEL CEKGEAVKEV QQSLTKAGKA AKLEKFELPA KIKLLSEPWT PESGLVTAAL KIKREQIKSK FKDELSKLYA