IPRI_HUMAN » Inositol 1,4,5-trisphosphate receptor-interacting protein

IPRI_HUMAN » Inositol 1,4,5-trisphosphate receptor-interacting protein
Magnify IPRI_HUMAN » Inositol 1,4,5-trisphosphate receptor-interacting proteinEnlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
IPRI_HUMAN » Inositol 1,4,5-trisphosphate receptor-interacting protein » Protein DANGER;
Hydrophobic Thickness 34.0 ± 1.6 Å
Tilt Angle 1 ± 2°
ΔGtransfer -21.3 kcal/mol
ΔGfold -8.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 82-105 (81-109)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 242-483, PDBID: 4WOY, Subunit B, Seq Identity:53%, Mab-21 protein

UniProt annotation for IPRI_HUMAN » Inositol 1,4,5-trisphosphate receptor-interacting protein
FUNCTION: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release.
UniProt features for IPRI_HUMAN » Inositol 1,4,5-trisphosphate receptor-interacting protein
SIGNAL 1 15

CHAIN 16 547 Inositol 1,4,5-trisphosphate receptor- interacting protein.

COILED 32 82

Amino Acid Sequence for IPRI_HUMAN » Inositol 1,4,5-trisphosphate receptor-interacting protein
MAMGLFRVCL VVVTAIINHP LLFPRENATV PENEEEIIRK MQAHQEKLQL EQLRLEEEVA RLAAEKEALE QVAEEGRQQN ETRVAWDLWS TLCMILFLMI EVWRQDHQEG PSPECLGGEE DELPGLGGAP LQGLTLPNKA TLGHFYERCI RGATADAART REFLEGFVDD LLEALRSLCN RDTDMEVEDF IGVDSMYENW QVDRPLLCHL FVPFTPPEPY RFHPELWCSG RSVPLDRQGY GQIKVVRADG DTLSCICGKT KLGEDMLCLL HGRNSMAPPC GDMENLLCAT DSLYLDTMQV MKWFQTALTR AWKGIAHKYE FDLAFGQLDS PGSLKIKFRS GKFMPFNLIP VIQCDDSDLY FVSHLPREPS EGTPASSTDW LLSFAVYERH FLRTTLKALP EGACHLSCLQ IASFLLSKQS RLTGPSGLSS YHLKTALLHL LLLRQAADWK AGQLDARLHE LLCFLEKSLL QKKLHHFFIG NRKVPEAMGL PEAVLRAEPL NLFRPFVLQR SLYRKTLDSF YEMLKNAPAL ISEYSLHVPS DQPTPKS