INA22_YEAST » Inner membrane assembly complex subunit 22

INA22_YEAST » Inner membrane assembly complex subunit 22
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
INA22_YEAST » Inner membrane assembly complex subunit 22 »
Hydrophobic Thickness 29.4 ± 2.6 Å
Tilt Angle 34 ± 3°
ΔGtransfer -21.6 kcal/mol
ΔGfold -9.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 40-65 (39-66)
Pathways none
PDB none
OPM none
Complexes none
Interactions

CASP, Complex: INA22:CASP, PubMed

CBP4, Complex: INA22:CBP4

INA17, Complex: INA22:INA17

Domains none
UniProt annotation for INA22_YEAST » Inner membrane assembly complex subunit 22
FUNCTION: Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.

SUBUNIT: Component of the inner membrane assembly (INA) complex, composed of INA17 and INA22. Interacts with a subset of F(1)F(0)- ATP synthase subunits of the F(1)-domain and the peripheral stalk.

MISCELLANEOUS: Present with 589 molecules/cell in log phase SD medium.

UniProt features for INA22_YEAST » Inner membrane assembly complex subunit 22
TRANSIT 1 26 Mitochondrion.
CHAIN 27 216 Inner membrane assembly complex subunit 22.
COILED 64 93
Amino Acid Sequence for INA22_YEAST » Inner membrane assembly complex subunit 22
MFMARQVLRN GLFLRSLAPI KITARTVASA NAGIKRKSRF DKTMIKPLLL VMIFGSILNA VIAEKRNIID MERKYKLKLD KLKELIRRVH DNNGKVDFDA DDELKLVNLR LGIVGKNATG MKEDETDIVV PKEESLEEIW QSIIDEAKKE VIEKTPDAGV KNKEGIVTDL NVLKDLEKSK KEDEKVYLSG DVHMMMNQPG DLNEIAKEHD KIPKFL