IMK2_ARATH » Probably inactive leucine-rich repeat receptor-like protein kinase IMK2

IMK2_ARATH » Probably inactive leucine-rich repeat receptor-like protein kinase IMK2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
IMK2_ARATH » Probably inactive leucine-rich repeat receptor-like protein kinase IMK2 » Protein INFLORESCENCE MERISTEM RECEPTOR-LIKE KINASE 2;
Hydrophobic Thickness 34.4 ± 3.8 Å
Tilt Angle 44 ± 2°
ΔGtransfer -30.9 kcal/mol
ΔGfold -27.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 456-484 (456-489)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 51-92, PDBID: 4MN8, Subunit A, Seq Identity:34%, Leucine rich repeat N-terminal domain

AA: 164-182, PDBID: 4J0M, Subunit B, Seq Identity:70%, Leucine Rich repeat

AA: 263-323, PDBID: 4MN8, Subunit A, Seq Identity:46%, Leucine rich repeat

AA: 335-395, PDBID: 4J0M, Subunit A, Seq Identity:46%, Leucine rich repeat

AA: 537-805, PDBID: 2NRU, Subunit B, Seq Identity:37%, Protein tyrosine kinase

UniProt annotation for IMK2_ARATH » Probably inactive leucine-rich repeat receptor-like protein kinase IMK2
TISSUE SPECIFICITY: Expressed in meristems, including roots, vegetative, inflorescence and floral meristems.

DOMAIN: The protein kinase domain is predicted to be catalytically inactive. Lacks the conserved Asp active site at position 661, which is replaced by an Asn residue.

UniProt features for IMK2_ARATH » Probably inactive leucine-rich repeat receptor-like protein kinase IMK2
SIGNAL 1 33 Potential.
CHAIN 34 836 Probably inactive leucine-rich repeat receptor-like protein kinase IMK2.
REPEAT 119 142 LRR 1.
REPEAT 143 166 LRR 2.
REPEAT 167 189 LRR 3.
REPEAT 191 212 LRR 4.
REPEAT 215 237 LRR 5.
REPEAT 240 261 LRR 6.
REPEAT 264 286 LRR 7.
REPEAT 288 310 LRR 8.
REPEAT 312 334 LRR 9.
REPEAT 336 358 LRR 10.
REPEAT 360 381 LRR 11.
REPEAT 384 406 LRR 12.
DOMAIN 537 808 Protein kinase.
Amino Acid Sequence for IMK2_ARATH » Probably inactive leucine-rich repeat receptor-like protein kinase IMK2
MNHLYKNPFR IYEISFHFCA SLLLCFLLFS AQAVAGGGGG GHSWDGIVVT QANYQALQAI KHELIDFTGV LKSWNNSASS QVCSGWAGIK CLRGQVVAIQ LPWKGLGGTI SEKIGQLGSL RKLSLHNNVI AGSVPRSLGY LKSLRGVYLF NNRLSGSIPV SLGNCPLLQN LDLSSNQLTG AIPPSLTEST RLYRLNLSFN SLSGPLPVSV ARSYTLTFLD LQHNNLSGSI PDFFVNGSHP LKTLNLDHNR FSGAVPVSLC KHSLLEEVSI SHNQLSGSIP RECGGLPHLQ SLDFSYNSIN GTIPDSFSNL SSLVSLNLES NHLKGPIPDA IDRLHNLTEL NLKRNKINGP IPETIGNISG IKKLDLSENN FTGPIPLSLV HLAKLSSFNV SYNTLSGPVP PVLSKKFNSS SFLGNIQLCG YSSSNPCPAP DHHHPLTLSP TSSQEPRKHH HRKLSVKDVI LIAIGALLAI LLLLCCILLC CLIKKRAALK QKDGKDKTSE KTVSAGVAGT ASAGGEMGGK LVHFDGPFVF TADDLLCATA EIMGKSTYGT AYKATLEDGN EVAVKRLREK TTKGVKEFEG EVTALGKIRH QNLLALRAYY LGPKGEKLLV FDYMSKGSLS AFLHARGPET LIPWETRMKI AKGISRGLAH LHSNENMIHE NLTASNILLD EQTNAHIADY GLSRLMTAAA ATNVIATAGT LGYRAPEFSK IKNASAKTDV YSLGIIILEL LTGKSPGEPT NGMDLPQWVA SIVKEEWTNE VFDLELMRET QSVGDELLNT LKLALHCVDP SPAARPEANQ VVEQLEEIRP ETEVETETTP FGSGGEGGKD LGSNEE