ILDR1_HUMAN » Immunoglobulin-like domain-containing receptor 1

ILDR1_HUMAN » Immunoglobulin-like domain-containing receptor 1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
ILDR1_HUMAN » Immunoglobulin-like domain-containing receptor 1 »
Hydrophobic Thickness 34.4 ± 2.6 Å
Tilt Angle 45 ± 0°
ΔGtransfer -32.7 kcal/mol
ΔGfold -27.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 158-190 (158-193)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 167-214, Lipolysis stimulated receptor (LSR)

UniProt annotation for ILDR1_HUMAN » Immunoglobulin-like domain-containing receptor 1
FUNCTION: Putative membrane receptor.

SUBUNIT: Homooligomer.

TISSUE SPECIFICITY: Mainly expressed in prostate and to a lower extent in testis, pancreas, kidney, heart and liver.

DISEASE: Deafness, autosomal recessive, 42 (DFNB42) OMIM: A prelingual, non-progressive form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. mutations affecting the gene represented in this entry.

UniProt features for ILDR1_HUMAN » Immunoglobulin-like domain-containing receptor 1
SIGNAL 1 23 Potential.
CHAIN 24 546 Immunoglobulin-like domain-containing receptor 1.
DOMAIN 24 162 Ig-like V-type.
DISULFID 45 145 By similarity.
Amino Acid Sequence for ILDR1_HUMAN » Immunoglobulin-like domain-containing receptor 1
MAWPKLPAPW LLLCTWLPAG CLSLLVTVQH TERYVTLFAS IILKCDYTTS AQLQDVVVTW RFKSFCKDPI FDYYSASYQA ALSLGQDPSN DCNDNQREVR IVAQRRGQNE PVLGVDYRQR KITIQNRADL VINEVMWWDH GVYYCTIEAP GDTSGDPDKE VKLIVLHWLT VIFIILGALL LLLLIGVCWC QCCPQYCCCY IRCPCCPAHC CCPEEALARH RYMKQAQALG PQMMGKPLYW GADRSSQVSS YPMHPLLQRD LSLPSSLPQM PMTQTTNQPP IANGVLEYLE KELRNLNLAQ PLPPDLKGRF GHPCSMLSSL GSEVVERRII HLPPLIRDLS SSRRTSDSLH QQWLTPIPSR PWDLREGRSH HHYPDFHQEL QDRGPKSWAL ERRELDPSWS GRHRSSRLNG SPIHWSDRDS LSDVPSSSEA RWRPSHPPFR SRCQERPRRP SPRESTQRHG RRRRHRSYSP PLPSGLSSWS SEEDKERQPQ SWRAHRRGSH SPHWPEEKPP SYRSLDITPG KNSRKKGSVE RRSEKDSSHS GRSVVI