IKU2_ARATH » Receptor-like protein kinase HAIKU2

IKU2_ARATH » Receptor-like protein kinase HAIKU2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
IKU2_ARATH » Receptor-like protein kinase HAIKU2 »
Hydrophobic Thickness 37.2 ± 2.8 Å
Tilt Angle 19 ± 8°
ΔGtransfer -31.8 kcal/mol
ΔGfold -24.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 613-637 (613-640)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 23-64, PDBID: 4MN8, Subunit A, Seq Identity:26%, Leucine rich repeat N-terminal domain

AA: 366-424, PDBID: 4MN8, Subunit A, Seq Identity:39%, Leucine rich repeat

AA: 436-496, PDBID: 4MN8, Subunit A, Seq Identity:42%, Leucine rich repeat

AA: 671-963, PDBID: 4F0F, Subunit A, Seq Identity:23%, Protein tyrosine kinase

UniProt annotation for IKU2_ARATH » Receptor-like protein kinase HAIKU2
FUNCTION: Modulates the seed size by negatively regulating the cellularization of syncytial endosperm.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Expressed in the endosperm of fertilized ovules.

UniProt features for IKU2_ARATH » Receptor-like protein kinase HAIKU2
SIGNAL 1 19 Potential.
CHAIN 20 991 Receptor-like protein kinase HAIKU2.
REPEAT 66 90 LRR 1.
REPEAT 99 123 LRR 2.
REPEAT 125 148 LRR 3.
REPEAT 150 170 LRR 4.
REPEAT 171 196 LRR 5.
REPEAT 197 220 LRR 6.
REPEAT 221 244 LRR 7.
REPEAT 246 267 LRR 8.
REPEAT 269 291 LRR 9.
REPEAT 292 314 LRR 10.
REPEAT 315 339 LRR 11.
REPEAT 341 363 LRR 12.
REPEAT 365 387 LRR 13.
REPEAT 388 411 LRR 14.
REPEAT 413 435 LRR 15.
REPEAT 436 459 LRR 16.
REPEAT 461 482 LRR 17.
REPEAT 483 508 LRR 18.
REPEAT 510 531 LRR 19.
REPEAT 532 554 LRR 20.
REPEAT 555 578 LRR 21.
DOMAIN 671 970 Protein kinase.
ACT_SITE 814 814 Proton acceptor (By similarity).
Amino Acid Sequence for IKU2_ARATH » Receptor-like protein kinase HAIKU2
MLRLLFIVRL LFLMPLASSR SNHSEEVENL LKLKSTFGET KSDDVFKTWT HRNSACEFAG IVCNSDGNVV EINLGSRSLI NRDDDGRFTD LPFDSICDLK LLEKLVLGNN SLRGQIGTNL GKCNRLRYLD LGINNFSGEF PAIDSLQLLE FLSLNASGIS GIFPWSSLKD LKRLSFLSVG DNRFGSHPFP REILNLTALQ WVYLSNSSIT GKIPEGIKNL VRLQNLELSD NQISGEIPKE IVQLKNLRQL EIYSNDLTGK LPLGFRNLTN LRNFDASNNS LEGDLSELRF LKNLVSLGMF ENRLTGEIPK EFGDFKSLAA LSLYRNQLTG KLPRRLGSWT AFKYIDVSEN FLEGQIPPYM CKKGVMTHLL MLQNRFTGQF PESYAKCKTL IRLRVSNNSL SGMIPSGIWG LPNLQFLDLA SNYFEGNLTG DIGNAKSLGS LDLSNNRFSG SLPFQISGAN SLVSVNLRMN KFSGIVPESF GKLKELSSLI LDQNNLSGAI PKSLGLCTSL VDLNFAGNSL SEEIPESLGS LKLLNSLNLS GNKLSGMIPV GLSALKLSLL DLSNNQLTGS VPESLVSGSF EGNSGLCSSK IRYLRPCPLG KPHSQGKRKH LSKVDMCFIV AAILALFFLF SYVIFKIRRD KLNKTVQKKN DWQVSSFRLL NFNEMEIIDE IKSENIIGRG GQGNVYKVSL RSGETLAVKH IWCPESSHES FRSSTAMLSD GNNRSNNGEF EAEVATLSNI KHINVVKLFC SITCEDSKLL VYEYMPNGSL WEQLHERRGE QEIGWRVRQA LALGAAKGLE YLHHGLDRPV IHRDVKSSNI LLDEEWRPRI ADFGLAKIIQ ADSVQRDFSA PLVKGTLGYI APEYAYTTKV NEKSDVYSFG VVLMELVTGK KPLETDFGEN NDIVMWVWSV SKETNREMMM KLIDTSIEDE YKEDALKVLT IALLCTDKSP QARPFMKSVV SMLEKIEPSY NKNSGEASYG ESANDEITKV V