HXK3_ARATH » Hexokinase-3

HXK3_ARATH » Hexokinase-3
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Topology in Chloroplast outer membrane
Topologyintermembrane space
cytoplasmic side
HXK3_ARATH » Hexokinase-3 »
Hydrophobic Thickness 34.8 ± 1.6 Å
Tilt Angle 1 ± 0°
ΔGtransfer -33.3 kcal/mol
ΔGfold -17.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 3-26 (3-32)
Pathways

GDP-glucose biosynthesis (BioCyc)

starch degradation I (BioCyc)

sucrose degradation III (BioCyc)

trehalose degradation II (trehalase) (BioCyc)

PDB none
OPM none
Complexes none
Interactions

HXK1, Complex: HXK1:HXK3

Domains

AA: 40-239, PDBID: 4QS7, Subunit A, Seq Identity:54%, Hexokinase

AA: 245-495, PDBID: 4QS7, Subunit A, Seq Identity:49%, Hexokinase

UniProt annotation for HXK3_ARATH » Hexokinase-3
FUNCTION: Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity).

CATALYTIC ACTIVITY: ATP + D-hexose = ADP + D-hexose 6-phosphate.

UniProt features for HXK3_ARATH » Hexokinase-3
CHAIN 1 498 Hexokinase-3.
REGION 170 196 Glucose-binding (Potential).
Amino Acid Sequence for HXK3_ARATH » Hexokinase-3
MGKVAVAFAA VAVVAACSVA AVMVGRRMKS RRKWRTVVEI LKELEDDCDT PVGRLRQVVD AMAVEMHAGL ASEGGSKLKM LLTFVDDLPT GREKGTYYAL HLGGTYFRIL RVLLGDQRSY LDVQDVERHP IPSHLMNSTS EVLFNFLAFS LERFIEKEEN GSDSQGVRRE LAFTFSFPVK HTSISSGVLI KWTKGFEISE MVGQDIAECL QGALNRRGLD MHVAALVNDT VGALSLGYYH DPDTVVAVVF GTGSNACYLE RTDAIIKCQG LLTTSGSMVV NMEWGNFWSS HLPRTSYDID LDAESSNAND MGFEKMISGM YLGDIVRRVI LRMSEDSDIF GPISPVLSEP YVLRTNSVSA IHEDDTPELQ EVARILKDIG VSDVPLKVRK LVVKICDVVT RRAGRLAAAG IAGILKKIGR DGSGGITSGR SRSEIQMQKR TVVAVEGGLY MNYTMFREYM EEALVEILGE EVSQYVVVKA MEDGSSIGSA LLVASLQS