HSL2_ARATH » LRR receptor-like serine/threonine-protein kinase HSL2

HSL2_ARATH » LRR receptor-like serine/threonine-protein kinase HSL2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
HSL2_ARATH » LRR receptor-like serine/threonine-protein kinase HSL2 » Protein HAESA-LIKE2;
Hydrophobic Thickness 34.8 ± 3.8 Å
Tilt Angle 22 ± 17°
ΔGtransfer -22.0 kcal/mol
ΔGfold -17.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 629-655 (627-656)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: HSL2:BETL2

Domains

AA: 24-67, PDBID: 4MN8, Subunit A, Seq Identity:39%, Leucine rich repeat N-terminal domain

AA: 172-194, PDBID: 3O53, Subunit B, Seq Identity:50%, Leucine Rich Repeat

AA: 532-554, PDBID: 3RGX, Subunit A, Seq Identity:48%, Leucine Rich Repeat

AA: 686-985, PDBID: 4OA2, Subunit A, Seq Identity:42%, Protein kinase domain

UniProt annotation for HSL2_ARATH » LRR receptor-like serine/threonine-protein kinase HSL2
FUNCTION: Receptor-like serine/threonine-kinase acting on substrates that controls floral organ abscission. Regulated by the "INFLORESCENCE DEFICIENT IN ABSCISSION" (IDA) family of ligands.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Expression is restricted to the abscission zone.

DEVELOPMENTAL STAGE: Expression increases shortly before the onset of abscission.

UniProt features for HSL2_ARATH » LRR receptor-like serine/threonine-protein kinase HSL2
SIGNAL 1 28 Potential.
CHAIN 29 993 LRR receptor-like serine/threonine- protein kinase HSL2.
REPEAT 75 96 LRR 1.
REPEAT 99 120 LRR 2.
REPEAT 124 146 LRR 3.
REPEAT 148 170 LRR 4.
REPEAT 172 192 LRR 5.
REPEAT 196 217 LRR 6.
REPEAT 221 243 LRR 7.
REPEAT 245 267 LRR 8.
REPEAT 269 291 LRR 9.
REPEAT 293 315 LRR 10.
REPEAT 316 338 LRR 11.
REPEAT 364 386 LRR 12.
REPEAT 388 410 LRR 13.
REPEAT 412 433 LRR 14.
REPEAT 435 458 LRR 15.
REPEAT 460 481 LRR 16.
REPEAT 484 507 LRR 17.
REPEAT 508 530 LRR 18.
REPEAT 532 555 LRR 19.
REPEAT 556 579 LRR 20.
REPEAT 580 601 LRR 21.
DOMAIN 686 992 Protein kinase.
ACT_SITE 817 817 Proton acceptor (By similarity).
Amino Acid Sequence for HSL2_ARATH » LRR receptor-like serine/threonine-protein kinase HSL2
MLTNTNLFFF LSLLLLSCFL QVSSNGDAEI LSRVKKTRLF DPDGNLQDWV ITGDNRSPCN WTGITCHIRK GSSLAVTTID LSGYNISGGF PYGFCRIRTL INITLSQNNL NGTIDSAPLS LCSKLQNLIL NQNNFSGKLP EFSPEFRKLR VLELESNLFT GEIPQSYGRL TALQVLNLNG NPLSGIVPAF LGYLTELTRL DLAYISFDPS PIPSTLGNLS NLTDLRLTHS NLVGEIPDSI MNLVLLENLD LAMNSLTGEI PESIGRLESV YQIELYDNRL SGKLPESIGN LTELRNFDVS QNNLTGELPE KIAALQLISF NLNDNFFTGG LPDVVALNPN LVEFKIFNNS FTGTLPRNLG KFSEISEFDV STNRFSGELP PYLCYRRKLQ KIITFSNQLS GEIPESYGDC HSLNYIRMAD NKLSGEVPAR FWELPLTRLE LANNNQLQGS IPPSISKARH LSQLEISANN FSGVIPVKLC DLRDLRVIDL SRNSFLGSIP SCINKLKNLE RVEMQENMLD GEIPSSVSSC TELTELNLSN NRLRGGIPPE LGDLPVLNYL DLSNNQLTGE IPAELLRLKL NQFNVSDNKL YGKIPSGFQQ DIFRPSFLGN PNLCAPNLDP IRPCRSKRET RYILPISILC IVALTGALVW LFIKTKPLFK RKPKRTNKIT IFQRVGFTEE DIYPQLTEDN IIGSGGSGLV YRVKLKSGQT LAVKKLWGET GQKTESESVF RSEVETLGRV RHGNIVKLLM CCNGEEFRFL VYEFMENGSL GDVLHSEKEH RAVSPLDWTT RFSIAVGAAQ GLSYLHHDSV PPIVHRDVKS NNILLDHEMK PRVADFGLAK PLKREDNDGV SDVSMSCVAG SYGYIAPEYG YTSKVNEKSD VYSFGVVLLE LITGKRPNDS SFGENKDIVK FAMEAALCYP SPSAEDGAMN QDSLGNYRDL SKLVDPKMKL STREYEEIEK VLDVALLCTS SFPINRPTMR KVVELLKEKK SLE