HERP2_HUMAN » Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

HERP2_HUMAN » Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
HERP2_HUMAN » Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein »
Hydrophobic Thickness 29.2 ± 2.2 Å
Tilt Angle 11 ± 4°
ΔGtransfer -15.6 kcal/mol
ΔGfold -4.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 301-319 (301-320)
Pathways none
PDB 2kdb (9-85)
OPM none
Complexes none
Interactions none
Domains

AA: 12-89, PDBID: 2KDB, Subunit A, Seq Identity:100%, Ubiquitin family

UniProt annotation for HERP2_HUMAN » Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
FUNCTION: Could be involved in the unfolded protein response (UPR) pathway.
UniProt features for HERP2_HUMAN » Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
CHAIN 1 406 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein.
DOMAIN 10 89 Ubiquitin-like.
Amino Acid Sequence for HERP2_HUMAN » Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
MDQSGMEIPV TLIIKAPNQK YSDQTISCFL NWTVGKLKTH LSNVYPSKPL TKDQRLVYSG RLLPDHLQLK DILRKQDEYH MVHLVCTSRT PPSSPKSSTN RESHEALTSS SNSSSDHSGS TTPSSGQETL SLAVGSSSEG LRQRTLPQAQ TDQAQSHQFP YVMQGNVDNQ FPGQAAPPGF PVYPAFSPLQ MLWWQQMYAH QYYMQYQAAV SAQATSNVNP TQPTTSQPLN LAHVPGEEPP PAPNLVAQEN RPMNENVQMN AQGGPVLNEE DFNRDWLDWM YTFSRAAILL SIVYFYSSFS RFIMVMGAML LVYLHQAGWF PFRQEGGHQQ APNNNAEVNN DGQNANNLEL EEMERLMDDG LEDESGEDGG EDASAIQRPG LMASAWSFIT TFFTSLIPEG PPQVAN