HERK_ARATH » Receptor-like protein kinase HERK 1

HERK_ARATH » Receptor-like protein kinase HERK 1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
HERK_ARATH » Receptor-like protein kinase HERK 1 » Protein HERCULES RECEPTOR KINASE 1;
Hydrophobic Thickness 39.2 ± 1.8 Å
Tilt Angle 1 ± 1°
ΔGtransfer -47.4 kcal/mol
ΔGfold -15.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 404-428 (398-432)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 33-380, Carbohydrate-binding protein of the ER

AA: 485-755, PDBID: 2NRU, Subunit B, Seq Identity:43%, Protein tyrosine kinase

UniProt annotation for HERK_ARATH » Receptor-like protein kinase HERK 1
FUNCTION: Receptor-like protein kinase required for cell elongation during vegetative growth, mostly in a brassinosteroid- (BR-) independent manner.

TISSUE SPECIFICITY: Expressed in most vegetative tissues, including leaves, stems and roots, especially in cell elongation regions.

INDUCTION: By brassinosteroids (BR).

UniProt features for HERK_ARATH » Receptor-like protein kinase HERK 1
SIGNAL 1 24 Potential.
CHAIN 25 830 Receptor-like protein kinase HERK 1.
DOMAIN 485 758 Protein kinase.
ACT_SITE 609 609 Proton acceptor (By similarity).
Amino Acid Sequence for HERK_ARATH » Receptor-like protein kinase HERK 1
MGIEKFETFI LISTISILLC ICHGFTPVDN YLINCGSPTN GTLMGRIFLS DKLSSKLLTS SKEILASVGG NSGSDIYHTA RVFTEVSSYK FSVTRGRHWV RLYFNPFDYQ NFKMGSAKFA VSSQSHVLLS DFTVTSSKVV KEYSLNVTTN DLVLTFTPSS GSFAFVNAIE VISIPDTLIT GSPRFVGNPA QFPDMSMQGL ETIHRVNMGG PLVASNNDTL TRTWVPDSEF LLEKNLAKSM SKFSTVNFVP GYATEDSAPR TVYGSCTEMN SADNPNSIFN VTWEFDVDPG FQYYFRFHFC DIVSLSLNQL YFNLYVDSMV AATDIDLSTL VDNTLAGAYS MDFVTQTPKG SNKVRVSIGP STVHTDYPNA IVNGLEIMKM NNSKGQLSTG TFVPGSSSSS KSNLGLIVGS AIGSLLAVVF LGSCFVLYKK RKRGQDGHSK TWMPFSINGT SMGSKYSNGT TLTSITTNAN YRIPFAAVKD ATNNFDESRN IGVGGFGKVY KGELNDGTKV AVKRGNPKSQ QGLAEFRTEI EMLSQFRHRH LVSLIGYCDE NNEMILIYEY MENGTVKSHL YGSGLPSLTW KQRLEICIGA ARGLHYLHTG DSKPVIHRDV KSANILLDEN FMAKVADFGL SKTGPELDQT HVSTAVKGSF GYLDPEYFRR QQLTDKSDVY SFGVVLFEVL CARPVIDPTL PREMVNLAEW AMKWQKKGQL DQIIDQSLRG NIRPDSLRKF AETGEKCLAD YGVDRPSMGD VLWNLEYALQ LQEAVIDGEP EDNSTNMIGE LPPQINNFSQ GDTSVNVPGT AGRFEESSID DLSGVSMSKV FSQLVKSEGR