GSPL_ECOLI » Putative type II secretion system protein L

GSPL_ECOLI » Putative type II secretion system protein L
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Topology in Bacterial Gram-negative inner membrane
Topologyextracellular side
cytoplasmic side
GSPL_ECOLI » Putative type II secretion system protein L » T2SS protein L; Putative general secretion pathway protein L;
Hydrophobic Thickness 27.6 ± 2.9 Å
Tilt Angle 17 ± 14°
ΔGtransfer -16.4 kcal/mol
ΔGfold -9.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 242-260 (238-263)
Pathways

Bacterial secretion system (KEGG)

PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 6-233, PDBID: 1W97, Subunit L, Seq Identity:21%, Type II secretion system (T2SS), protein L

AA: 237-386, PDBID: 2W7V, Subunit A, Seq Identity:10%, GspL periplasmic domain

UniProt annotation for GSPL_ECOLI » Putative type II secretion system protein L
FUNCTION: Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.

INDUCTION: Silenced by the DNA-binding protein H-NS under standard growth conditions.

MISCELLANEOUS: Part of a cryptic operon that encodes proteins involved in type II secretion machinery in other organisms, but is not expressed in strain K12.

UniProt features for GSPL_ECOLI » Putative type II secretion system protein L
CHAIN 1 387 Putative type II secretion system protein L.
Amino Acid Sequence for GSPL_ECOLI » Putative type II secretion system protein L
MPESLMVIRS SSTLRKHWEW MTFSADSVSS VHTLTDDLPL ESLADQPGAG NVHLLIPPEG LLYRSLTLPN AKYKLTAQTL QWLAEETLPD NTQDWHWTVV DKQNESVEVI GIQSEKLSRY LERLHTAGLN VTRVLPDGCY LPWEVDSWTL VNQQTSWLIR SAAHAFNELD EHWLQHLAAQ FPPENMLCYG VVPHGVAAAN PLIQHPEIPS LSLYSADIAF QRYDMLHGIF RKQKTVSKSG KWLARLAVSC LVLAILSFVG SRSIALWHTL KIEDQLQQQQ QETWQRYFPQ IKRTHNFRFY FKQQLAQQYP EAVPLLYHLQ TLLLEHPELQ LMEANYSQKQ KSLTLKMSAK SEANIDRFCE LTQSWLPMEK TEKDPVSGVW TVRNSGK