GSPH_ECOLI » Putative type II secretion system protein H

GSPH_ECOLI » Putative type II secretion system protein H
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Topology in Bacterial Gram-negative inner membrane
Topologyextracellular side
cytoplasmic side
GSPH_ECOLI » Putative type II secretion system protein H » T2SS protein H; Protein transport protein HofH;Putative general secretion pathway protein H;
Hydrophobic Thickness 28.8 ± 1.6 Å
Tilt Angle 0 ± 0°
ΔGtransfer -37.3 kcal/mol
ΔGfold -19.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 7-31 (7-33)
Pathways

Bacterial secretion system (KEGG)

PDB 2knq (30-169)
OPM none
Complexes none
Interactions

EXBD, Complex: GSPH:EXBD, PubMed

Domains

AA: 1-27, Prokaryotic N-terminal methylation motif

AA: 43-157, PDBID: 2KNQ, Subunit A, Seq Identity:100%, Type II transport protein GspH

UniProt annotation for GSPH_ECOLI » Putative type II secretion system protein H
FUNCTION: Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.

INDUCTION: Silenced by the DNA-binding protein H-NS under standard growth conditions.

MISCELLANEOUS: Part of a cryptic operon that encodes proteins involved in type II secretion machinery in other organisms, but is not expressed in strain K12.

UniProt features for GSPH_ECOLI » Putative type II secretion system protein H
PROPEP 1 6 By similarity.
CHAIN 7 169 Putative type II secretion system protein H.
Amino Acid Sequence for GSPH_ECOLI » Putative type II secretion system protein H
MNQQRGFTLL EMMLVLALVA ITASVVLFTY GREDVASTRA RETAARFTAA LELAIDRATL SGQPVGIHFS DSAWRIMVPG KTPSAWRWVP LQEDAADESQ NDWDEELSIH LQPFKPDDSN QPQVVILADG QITPFSLLMA NAGTGEPLLT LVCSGSWPLD QTLARDTRP