GOSR1_YEAST » Golgi SNAP receptor complex member 1

GOSR1_YEAST » Golgi SNAP receptor complex member 1
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Topology in Golgi apparatus membrane
TopologyGolgi lumenal side
cytoplasmic side
GOSR1_YEAST » Golgi SNAP receptor complex member 1 » Golgi SNARE protein 1;Protein transport protein GOS1;
Hydrophobic Thickness 33.4 ± 2.6 Å
Tilt Angle 4 ± 3°
ΔGtransfer -23.8 kcal/mol
ΔGfold -15.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 202-223 (199-223)
Pathways

SNARE interactions in vesicular transport (KEGG)
PDB none
OPM none
Complexes none
Interactions

BET1, Complex: GOSR1:BET1, PubMed

BOS1, Complex: GOSR1:BOS1, PubMed

CALX, Complex: CALX:GOSR1

CASP, Complex: GOSR1:CASP, PubMed

EPS1, Complex: GOSR1:EPS1

GDA1, Complex: GDA1:GOSR1

GPI8, Complex: GOSR1:GPI8

HOC1, Complex: GOSR1:HOC1

KEX2, Complex: GOSR1:KEX2

KTR3, Complex: KTR3:GOSR1, PubMed

MMM1, Complex: GOSR1:MMM1

MNN11, Complex: MNN11:GOSR1

MNN2, Complex: GOSR1:MNN2

MSMO, Complex: GOSR1:MSMO

MSP1, Complex: MSP1:GOSR1

OST1, Complex: GOSR1:OST1

OSTB, Complex: GOSR1:OSTB

PEP12, Complex: PEP12:GOSR1, PubMed

PSD1, Complex: PSD1:GOSR1

SCS2, Complex: GOSR1:SCS2

SEC22, Complex: SEC22:GOSR1, PubMed

SED5, Complex: SED5:GOSR1, PubMed

SFT1, Complex: GOSR1:SFT1, PubMed

TLG1, Complex: TLG1:GOSR1

TLG2, Complex: TLG2:GOSR1, PubMed

VAM3, Complex: VAM3:GOSR1

VOA1, Complex: GOSR1:VOA1

VTI1, Complex: GOSR1:VTI1

YD121, Complex: GOSR1:YD121
Domains

AA: 136-201, PDBID: 1GL2, Subunit C, Seq Identity:13%, Snare region anchored in the vesicle membrane C-terminus
UniProt annotation for GOSR1_YEAST » Golgi SNAP receptor complex member 1
FUNCTION: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. Rescues alpha- factor maturation defects.

SUBUNIT: Component of several multiprotein Golgi SNARE complexes. Identified in a Golgi SNARE complex consisting of t-SNARES SED5, YKT6, and the v-SNARE SFT1. Interacts with BET1. Interacts with BOS1. Interacts with SEC22. Interacts with PEP12. Interacts with self.

UniProt features for GOSR1_YEAST » Golgi SNAP receptor complex member 1
CHAIN 1 223 Golgi SNAP receptor complex member 1.
Amino Acid Sequence for GOSR1_YEAST » Golgi SNAP receptor complex member 1
MSSQPSFVTI RGKAISLETQ TESLLSKYST FAQTTSSEQT GQEKKIDKQL EGILGQRQDV IDSLTQICDS NPAISASKLS QLHRHKEILQ DHWKSFRNIR SSIQQERNRL NLLFSVKNDI ANSTTDAPAP IGDADEYIQN ETRRIDQSNN VVDRLISQAW ETRSQFHSQS NVLNTANNKV LQTLQRIPGV NQLIMKINTR RKKNAFVLAT ITTLCILFLF FTW