GI24_HUMAN » Platelet receptor Gi24

GI24_HUMAN » Platelet receptor Gi24
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
GI24_HUMAN » Platelet receptor Gi24 »
Hydrophobic Thickness 38.0 ± 4.2 Å
Tilt Angle 2 ± 1°
ΔGtransfer -26.1 kcal/mol
ΔGfold -19.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 192-218 (185-222)
Pathways none
PDB none
OPM none
Complexes none
Interactions

PLS1, Complex: GI24:PLS1, PubMed

Domains

AA: 40-169, PDBID: 3BI9, Subunit X, Seq Identity:21%, Immunoglobulin V-set domain

UniProt annotation for GI24_HUMAN » Platelet receptor Gi24
FUNCTION: May stimulate MMP14-mediated MMP2 activation.
UniProt features for GI24_HUMAN » Platelet receptor Gi24
SIGNAL 1 32
CHAIN 33 311 Platelet receptor Gi24.
DOMAIN 33 162 Ig-like.
DISULFID 54 146 By similarity.
Amino Acid Sequence for GI24_HUMAN » Platelet receptor Gi24
MGVPTALEAG SWRWGSLLFA LFLAASLGPV AAFKVATPYS LYVCPEGQNV TLTCRLLGPV DKGHDVTFYK TWYRSSRGEV QTCSERRPIR NLTFQDLHLH HGGHQAANTS HDLAQRHGLE SASDHHGNFS ITMRNLTLLD SGLYCCLVVE IRHHHSEHRV HGAMELQVQT GKDAPSNCVV YPSSSQESEN ITAAALATGA CIVGILCLPL ILLLVYKQRQ AASNRRAQEL VRMDSNIQGI ENPGFEASPP AQGIPEAKVR HPLSYVAQRQ PSESGRHLLS EPSTPLSPPG PGDVFFPSLD PVPDSPNFEV I