GFRAL_HUMAN » GDNF family receptor alpha-like

GFRAL_HUMAN » GDNF family receptor alpha-like
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
GFRAL_HUMAN » GDNF family receptor alpha-like »
Hydrophobic Thickness 28.4 ± 3.8 Å
Tilt Angle 1 ± 2°
ΔGtransfer -28.6 kcal/mol
ΔGfold -15.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 352-375 (350-382)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 131-210, PDBID: 2V5E, Subunit A, Seq Identity:34%, GDNF/GAS1 domain

AA: 220-316, PDBID: 2GH0, Subunit A, Seq Identity:20%, GDNF/GAS1 domain

UniProt features for GFRAL_HUMAN » GDNF family receptor alpha-like
SIGNAL 1 18 Potential.
CHAIN 19 394 GDNF family receptor alpha-like.
Amino Acid Sequence for GFRAL_HUMAN » GDNF family receptor alpha-like
MIVFIFLAMG LSLENEYTSQ TNNCTYLREQ CLRDANGCKH AWRVMEDACN DSDPGDPCKM RNSSYCNLSI QYLVESNFQF KECLCTDDFY CTVNKLLGKK CINKSDNVKE DKFKWNLTTR SHHGFKGMWS CLEVAEACVG DVVCNAQLAS YLKACSANGN PCDLKQCQAA IRFFYQNIPF NIAQMLAFCD CAQSDIPCQQ SKEALHSKTC AVNMVPPPTC LSVIRSCQND ELCRRHYRTF QSKCWQRVTR KCHEDENCIS TLSKQDLTCS GSDDCKAAYI DILGTVLQVQ CTCRTITQSE ESLCKIFQHM LHRKSCFNYP TLSNVKGMAL YTRKHANKIT LTGFHSPFNG EVIYAAMCMT VTCGILLLVM VKLRTSRISS KARDPSSIQI PGEL