GDT9_DICDI » Probable serine/threonine-protein kinase gdt9

GDT9_DICDI » Probable serine/threonine-protein kinase gdt9
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
GDT9_DICDI » Probable serine/threonine-protein kinase gdt9 » Growth-differentiation transition protein 9;Protein kinase Dusty;
Hydrophobic Thickness 34.8 ± 5.2 Å
Tilt Angle 19 ± 14°
ΔGtransfer -24.7 kcal/mol
ΔGfold -21.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 965-990 (959-994)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 1290-1569, PDBID: 4XI2, Subunit A, Seq Identity:47%, Protein tyrosine kinase

UniProt annotation for GDT9_DICDI » Probable serine/threonine-protein kinase gdt9
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
UniProt features for GDT9_DICDI » Probable serine/threonine-protein kinase gdt9
SIGNAL 1 16 Potential.
CHAIN 17 1577 Probable serine/threonine-protein kinase gdt9.
DOMAIN 1290 1573 Protein kinase.
ACT_SITE 1436 1436 Proton acceptor (By similarity).
Amino Acid Sequence for GDT9_DICDI » Probable serine/threonine-protein kinase gdt9
MKTFLLIFLL ICVCKGITNI TTPSIYFDLK KINRFQDYLN NGITPSINLT FHDFYYPDVC VNTIKNIDGS TNFVKSSFLN APTNFANLYI TKGSKMTVKP NQILGAFINI LCIEGSLEVP VGVFPFFIGA LVILPGGNFK SESSFRFMNL VNSKIDPLNF FPGILTLGGS LSILGPKSIK YSANRLGDFQ FQLLELIDPN SFNSDYKANI YSESFVTGQQ CDFVSITNGY TLTVGGCQGV PSTDVNIYIF FATVDYDCTF IDSDSEVPAS IYISGDTNVH IENFFLNSLG KTTNANYNDT ILIFSPTDDT NVTDIIIGTN QRYRNSLFVE FSNNVTLRNN FIRESIESRS PLMFFASSPI LEGNLVVSNS GSSVIAQFGT EFIQSTNNSY FLEPPTQPVI PNDNNMDYGT EGNGIYSLSP IVSFTTDVFV GQLISINFNF IANRSLVTGF NYDCFAPCYP GSPIISNLVQ HSVDFNIIKP TFSYSHGNTT SSTTTSSTTT NTNSHFLLNV NDNGNEPSSY YSFNQLSIAS EAIKVNLPIG TLGIGNLFAT NNFKIDGALE RLDILNSIFN LPPPISNNFS QSGILLSTTT SMLNSYVFVS IGSEPTRIES QIYGSTITPY YYNNIETLDL FQIQSIFPSV QYQIIKNSTI NITINITTTT TTTTTPTTNN VVCSFTSIVN QQSSVTNEIS INETLIQMDP ILNNCVFPLS IDQEGSLKLR VTIKNQNSTL ENQYYYIIDF PEITIFQSFQ FYTGIKFIDV QSSSSSSQQT SSFSPTTTTF LNLLSTTENS NGFLNGCQIS NQCTLSNNVK YVSSLPNVTN SPDFQLFQSG ITPIIPYDPV VINLGIEKNK TFQFQLFFTF YQPIDQYSSP LSIFIQSEPY LLLDPLIDAP NFKNFTFFYD NLNQDSIEIS FISRGDIYLT SMAIYSLDLV SYESSDSSSS SSNSSSSTGN GIGDIVNNED NHKKLVIALS VSIPVAALLV ILCFGIFICY NNNKKNKNET KGKDIETNTD KKDDENENEN CKFQFKDEFL TNPNEINIQL KKLMINKSST LPPQSTISID TSPSSENTTF TESLTPKKSA TVNGEIDFSR NSTNESTVSN SSSENNSDNN NNNNNKCKKE KLSSFPTIPG TNLTNIPLNL VGRKSRNPED KYRTNNDILV CLQESHYFKP DDPSIPIEFS ESVLDFGRGS KCLIDETYIY TISVKNKSTT DYNILLILPI DNNTGTISTD TQYFQINAGE SKPISFSISL NCTTKYFEKI GVSIEELNYH TFICVHMESE LSTRLDFSEL DFDEICGQGT YGMVYKGKWR SQVVAIKMMR VGTVNCDEVY REMDIMGKIR HQNVISFIGC VVSLEHLCIV TEFSPIGSLG DLIHGDNNQK KSNTNTITNT ITNTNTNTNT STSTSTKLTV KQKLRIAIDI ARGCQFLHQC GIIHRDLKPD NVLVFDINHN APVCAKISDF GTSKETNEFS NKNTNCVGTP IYMSNEILEK KTYDNSTDVY SFAVLFYEMM IEEVPFSEID EKWEIPSKVI SGWRPTKGLN SLDRDIKNLI NICWAPHSLP SFDEIVFSLV KIFKRFN