GDT8_DICDI » Probable serine/threonine-protein kinase gdt8

GDT8_DICDI » Probable serine/threonine-protein kinase gdt8
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
GDT8_DICDI » Probable serine/threonine-protein kinase gdt8 » Growth-differentiation transition protein 8;
Hydrophobic Thickness 40.0 ± 3.0 Å
Tilt Angle 8 ± 4°
ΔGtransfer -27.0 kcal/mol
ΔGfold -21.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 779-806 (777-811)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 1048-1290, PDBID: 4I92, Subunit A, Seq Identity:38%, Protein tyrosine kinase

UniProt annotation for GDT8_DICDI » Probable serine/threonine-protein kinase gdt8
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
UniProt features for GDT8_DICDI » Probable serine/threonine-protein kinase gdt8
SIGNAL 1 22 Potential.
CHAIN 23 1326 Probable serine/threonine-protein kinase gdt8.
DOMAIN 1036 1292 Protein kinase.
ACT_SITE 1158 1158 Proton acceptor (By similarity).
Amino Acid Sequence for GDT8_DICDI » Probable serine/threonine-protein kinase gdt8
MINKILIKLI TIIIFCFSFL FAEEDLIRTP PGYYNLTRHK RYPHITEYQS SQDTDLYYPD VCRNALRNDI IPGVDEFFPF LFPGFNSDGP NSIYIQKNSS LLFKSESLGT TYNFVAVCVE GSFTVKGSMF FTINSLIILP GGRFESEAGI EFYDENDPLH IYNNPDFPKD PFGFFPGILV LGGTISVVAK ESLVYRADRI SNSSIEISPP FSPMNKINQT IRIFTELYPL GFYCSFSSDL ERKILSLLDC LPISENDKII RVLIEVDRDQ NVSPTNILKK GKTTKGSIYI TGDSNVYFKN MFFKNLGFTT NEPYNDTKLI FSPNDPNQVT DIIMGTNQRF RSSLYIEFSK NVTIDGCAFF EDNLTRSPLV LFDSNVIISN SLISSKSGSN IIAQYGTESI QSSNNSYILV KIDTASLDVD QNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN MDYGNQGNGI YSISPNINSN GDSFFGQQYA FNYYFISKNS VNSNQDNSSL LNSKPIELII IDSSFNPTNS NGSLNKYLLN INSDGNKTIS TYLVCNSIIE YYSGWLMDNL NSNQQISFEG NLFQNGCNKV DGNCTISQNS KYSTDLPKVA NQTKFDEIVQ LDKLFSNGIT SINPNEKVII STKINSKIHY YQIQLFFTHL PIDDQPTPLS IYIENQPVFL LEPIKSTFPT FNNFTFKFEN KNSLDKINIA FTTRGDIYLT SMATYSSIVV EPPTETPTET PTETPTETPT DTPTQTPTQT PILTSKPITQ ISVDRNENLE LKIALPICLS LALLIGIIIM ICIFKKVQSN SKLKKDDDEN EMATIKEGNK SIIVSQPPTV IEEKPQDNSK PDDQKLIERD QQINNPILKI REYPSLKDIE LSNEETKSPQ YGSLNSFSTL QFSRQYDYGS EEFPFQFNKQ VLEFNLNGRK CMNDEVINDS LMIHNKSEIT YLVNIIFPQN IETGCVSILN VEIFNESFEL LPHCTTEVKF SLTLTCTTKF LENFAVLVEA QGSKCHTFLS VHVESETSLK LDYKEIKTEQ LIASYLPSKV YVFKGYYRDL AVAVKKFAIS DNSKSFEKIK NEVQILSKVN NINVVRYIGS AQNISHVCIV TEYAKEGSLG SLIHDSKIKL SFIQKVKFML DAAKGFTFLH ASEIVHGDIK PDNLLVFSKE ISGVCVKICD FGNSEELGEK ESKSKPDSTM NYLPNEVFDG EGYQKSADVY AFGVSLYEVM VEKIPFHEIC YNDIPNRVQD GFRPTADLDT IDDDIRKIIE CCWIKEKSKR PSFSEISLHL EIKFSKLLHQ MNESEESTSN HNTNSKTKED KDLDEN