GDT4_DICDI » Probable serine/threonine-protein kinase gdt4

GDT4_DICDI » Probable serine/threonine-protein kinase gdt4
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
GDT4_DICDI » Probable serine/threonine-protein kinase gdt4 » Growth-differentiation transition protein 4;
Hydrophobic Thickness 34.8 ± 3.0 Å
Tilt Angle 38 ± 0°
ΔGtransfer -22.6 kcal/mol
ΔGfold -21.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 888-916 (888-920)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 1349-1600, PDBID: 3SXR, Subunit B, Seq Identity:45%, Protein tyrosine kinase

UniProt annotation for GDT4_DICDI » Probable serine/threonine-protein kinase gdt4
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
UniProt features for GDT4_DICDI » Probable serine/threonine-protein kinase gdt4
SIGNAL 1 19 Potential.
CHAIN 20 1620 Probable serine/threonine-protein kinase gdt4.
DOMAIN 1349 1604 Protein kinase.
ACT_SITE 1466 1466 Proton acceptor (By similarity).
Amino Acid Sequence for GDT4_DICDI » Probable serine/threonine-protein kinase gdt4
MKLEQRIFFL ICLVINSFSN CSLLVAPDGY YNIYRENKIE NILNLKPNGN KSQDSYYPDV CSKAVKNKEG VKSFILSSFP LSTKEYANVI VTKGSHMTLG DGEYHQIFNI NRFLNIVCVE GSLVFSTKDV VYMSALVILP GGNFECIDCT IKFRDLYPTN SLIDPFGFLP GIITLGGSLS LLGKQKTVYS AVLIDENILE VQDISSLDIF NGYSLFIFSE SFPLGKASTF TFNSNQIKVL EIKIPKTDKS IRVFFYSRFS TFSTSTTASI HITGNSNVHI ENFYIDSFGR TTNDQYSDTE LIFSQDDPNL ITGFINGSNQ RFRSSLYIEH SNNVTIKNSV ILENRGETRS PLIFFGSNVN ISGNIISSKS GSSLIAQYGT ENIQSTNNYY SLSLPLLKSL NSTLDSMDYG NEGNGIFSIS PKINSINDIF NGQIIAINHI ILSDRSSITG FDKDCYSPCY NDSIRVSSKV QHSVEFKITG STFISSSNYS ESSFLFRISE TGSKQSSFYK IINSNLSYPI SVLLENNAFI LDNVYGFGNF TINGLIKRLD IINSTLDPSV TSSISLSNFS KAISIQNSFM DYRSFQKQNN QIYGSIITPY LYYFENTMNL IKVSKMYPNV NHQILAGTVL NMGIEIIIIA PLFGKMDCIF EDESGIQTIP FNKSSNSCVL PYLFKNEGSF NVRVTLSLTK SLDNIIFQVY FPMVTVFNIY SFYSGWAMID SNIEKEIIID GNIFKKGCQQ QVLGNCTIST NSKLITGLPS VTESDKLNRL FSSGITSINP YEPVTITIPI DKESKKNQIQ LFFTHQPIDI ETSLLSIYVE NQPIFLLEPL QSNLDSTFKN LTFHYENSKS LEKIKITFIT RGDIYLTSTA IYSSTNQPIY NEVIGINEQL NILAIVLPIT ISLFAAASIL AGYLVIKKYK KPNMYYNRNT NGNIGMKVFS TKFKRRPKKV IPLSIPLSTN RITKKSLQSL DSMAENPVIL LSIPELEKAN EPEFNPEKTF LQESELLDLP TPKVEPEEPR INIVPLPRFP TVYKKEDNDK LLKELNITGP ITSENIESFF EVDVGLPSLI IKNESEIILQ EIDYIETGEI QEMEGSFLED KSTDTTVIVT KSDGLPKFFQ TKVFSKRFND ISKFDNDFFD LKEYIVEHQE ESFEIPFMTS EDEVDETKIN IIDFLLSPKS NKVALNMYLK SFQNRNHKLC YGKYGSNKNS ILVIEGTSYY YDCTDVRLPI STPRSNLNFG ITDGNKCIVD RKYRERLQYI NVYSEPFRIY TLFPDSNDNV TITTSECCKE IDPFGSLDVD IFVTLKTTTK FNEKVTIRYE TDDKELAFST FVYLNLESQV SSKIDFDEIV LEKYLSEGSF GVVYSAIWRS SSVAVKLFKH HYSKDEIDKE TSILSKIKHP NIVSFIGSLN FLNTYGIVID YHPRGSLNYY TRNQNIKLSM VQNIRISLDI SRACSFLHKN GIIHRDLKPD NVLIVSFDPD SSICAKISDF GTCREINGKH ELNSKAGTTR YMSPEILEGL PYTYSTDVYS FAILFFELLS GRVPFREIPK REIPRFVRLG TRPRLDQDVF ADNDISLILL ACWNPNPRGR PTFDTLIDLL EKLLKKYKER AKRNKKNQNQ