GDT2_DICDI » Probable serine/threonine-protein kinase gdt2

GDT2_DICDI » Probable serine/threonine-protein kinase gdt2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
GDT2_DICDI » Probable serine/threonine-protein kinase gdt2 » Growth-differentiation transition protein 2;
Hydrophobic Thickness 41.2 ± 4.6 Å
Tilt Angle 7 ± 6°
ΔGtransfer -31.2 kcal/mol
ΔGfold -22.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 894-922 (894-927)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 1290-1542, PDBID: 1BYG, Subunit A, Seq Identity:41%, Protein tyrosine kinase

UniProt annotation for GDT2_DICDI » Probable serine/threonine-protein kinase gdt2
FUNCTION: Regulates the transition between growth and differentiation.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

DEVELOPMENTAL STAGE: Expressed at the same level in vegetative cells and throughout development, with a slight peak at the time when the cells are aggregating.

UniProt features for GDT2_DICDI » Probable serine/threonine-protein kinase gdt2
SIGNAL 1 19 Potential.
CHAIN 20 1637 Probable serine/threonine-protein kinase gdt2.
DOMAIN 1290 1547 Protein kinase.
ACT_SITE 1408 1408 Proton acceptor (By similarity).
Amino Acid Sequence for GDT2_DICDI » Probable serine/threonine-protein kinase gdt2
MNYILYILLI LIIFSINNTF SIGSFVYTPD GYYNLYRINK FENFSKIPTK ANSVNVEPHE LYYPDICDSA LKNKNSNEFS IDNFPGSPFL KANIKITKGS NMTLDPLLSI HPSYINILCI EGSFTAGSQQ TLTLGGIIVL PGGNFHCNNC VLQFVDLSST IIKIDPFGFL PGILSLGGSI SLIGSQRILY SAKPIEDNVL EVNDISTLDP FNGFNVSIVS DSFPNVRTSR FTYNKNKLEM QDLTIPTTDL NIKLFFNDSG SLKFGGISTR TKSSIYITGD TKLHIENYLL DSIGKTSNKE YDDTKLTFSS DNPNNVTDII IGKNQRFRNS LYIEFSNSVT IKNSVIIGNT GSSRSSLVFF QSNVNISGNL IVGTAGSSMI AQYGTEYIES SNNYFSLVLP NEFPTSPAFM DYGHEGNGIY SLSPNIFSTN DIFNGQKILY NFNFISRENV TGFDKDCFAP CDINSIVVPS LSQEPIDFSK NLVNPISINP VDYFLIVNSD EELKNTFFTI KDSTISSKII VNLKGSGLVL KNIIGVNNFK LTGQVKRLDI YDSFFGSSTT PSLGDNGIKS SAVIIKNSSF YIDDFQLQNN QIYGSSIVPY LYELLNVDEF ILVDSIFPTS QYQIPVGGKL DLIVKLVIIS PVISRITCEL ESDNETITSS AISESVNKEC KFPLTFKNDG SVNLKVTVKL KNVGDSEIMY IINFPKITIF SNYSFYSGWS MENSTENGII SVDGNSFKKG CSISSNDNSN NCTISNNIKY ITNLPKLNIS NDLNELFLNG ITSINSNELV TITTRIDSET KYYQIQLFFI HQPIDDQPTP LSIYIENQPV FLLEPLESNS APIFKNLTFN FDNINSLENI NISFATRGNT YLTSMAIYSS LVIEYPIPVE KINLLPIIVP ICVTVLVLLS ILIVFFGARY YKHKKRRRLE IAVFGVELYS KKPSNNKSPV PSTPLIINSN QEQSSSNHIS ITVNRNSDIQ TQSENNNLEP TTVETTTTTT TTAAGAILQT NVTLEMENLE IKPIINNNEP FFEDYSDEYD DSSDGAELNE DDVEDYINII RGGNIKIEAE GELFVRQFER NTFDQEFFEY KKSKIPSPHL VPSLAHGDFI ENPLNIIDIL LDPVTNEIPL EHYLKTYKNR NGQSGKYRTN TQTHVLIADT IFQHCNDPDL PVSVSPYICD FGMNGRKSDL GEVCHDTITF KNKLSEPLYA LFLFPEGDDS SITSSPFQSI ELKPNVETSI SLSVTLFSTT KYNEKVIVRF ETLDVKQSWS TFVFLRLESE LTNIIDFNEI IIKNYISEGT FGIVYRGIWR SSPVAVKLLK NEYVDHDEIE KEISLLERLR HPNILLYVGR FIFSGIHGIV TDYCSKGCLS KYIHENKYKI TIIQKIRILI DISKACAYLH RNGITHRDLK PENILITSLN PKSLVCAKVS DFGTSKETNE RYNLQTRRGT VAYMSNEILS QGSYTKSTDI YSFGMLCYEL FSERIPYYSE PHWRIRELVL KNERPSLDQE IFKDTDISDI VTRCWSKNPS QRPTFDYLSK YLKHLLKKYD INNIIYDKDK KNKKKNKNNN NNNNNNNNNN NNNNNNNNNN DDHDDNNNNI NDSDCDNNKN NNNNNNNNNN NNNNNNNNNN NNNNNNN