GACV_DICDI » Rho GTPase-activating protein gacV

GACV_DICDI » Rho GTPase-activating protein gacV
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Topology in Membrane
Topologyouter side
inner side
GACV_DICDI » Rho GTPase-activating protein gacV » GTPase activating factor for raC protein V;
Hydrophobic Thickness 31.0 ± 3.0 Å
Tilt Angle 10 ± 10°
ΔGtransfer -19.0 kcal/mol
ΔGfold -13.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 10-30 (5-35)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 223-438, PDBID: 2MBG, Subunit A, Seq Identity:15%, RhoGAP domain

UniProt annotation for GACV_DICDI » Rho GTPase-activating protein gacV
FUNCTION: Rho GTPase-activating protein involved in the signal transduction pathway.
UniProt features for GACV_DICDI » Rho GTPase-activating protein gacV
CHAIN 1 520 Rho GTPase-activating protein gacV.
DOMAIN 195 472 Rho-GAP.
COILED 28 192 Potential.
COILED 480 520 Potential.
Amino Acid Sequence for GACV_DICDI » Rho GTPase-activating protein gacV
MSNNSNNNIK TYYIIGIITL IFIVSAVIKN QLSSSNQEQQ EEEEETDSMG KSKGRGNKKG KKPEKIQEKK LDNHLKNLEK VKLQEDFKLQ QDEKQQLKKE ETILVEKQEI VVDELKNKKD EEKQQQQQEE DQQQQQQQQQ EEEEEEEEQQ EIEEDEEEEE GQEQEEEEEQ QEIEEGEEEQ QEEEQEEEQF SMFGVSIERL MDFQRQEDEN EGSDEVEESS KVPIVLSFML DRIKNLNGFK TEGLFRVNGN LKLVEQLATE GFDPFSDDLD PNVNTWASLL KKWIRDLPEP LIPHELNPII LDFCTNNNIN NTCNNNNDNN NNNNFNVCAS TNNLGNVLNL STNICNNNNN NNNNNNNNNN NNNNNDNNNN NNESIEKKIT NIINMIKSDD HRNVLYKIGE FFGEMLQEET VLITKINVES LSKILTPSLF KPNNIIDDFS NGSLNGSGNQ IPKYLTTLDL PSILLKQKKE IAFVSCLLNY FKDEYSKKLQ EQNDQEEDNQ EEEKDNQEED EDEEDKDQEE