FUS1_YEAST » Nuclear fusion protein FUS1

FUS1_YEAST » Nuclear fusion protein FUS1
Magnify FUS1_YEAST » Nuclear fusion protein FUS1Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
FUS1_YEAST » Nuclear fusion protein FUS1 »
Hydrophobic Thickness 36.4 ± 1.4 Å
Tilt Angle 0 ± 0°
ΔGtransfer -51.1 kcal/mol
ΔGfold -16.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 70-95 (67-98)
Pathways

MAPK signaling pathway - yeast (KEGG)

PDB none
OPM none
Complexes none
Interactions

ALG1, Complex: ALG1:FUS1, PubMed

PBN1, Complex: FUS1:PBN1, PubMed

PRM4, Complex: FUS1:PRM4, PubMed

VAC7, Complex: FUS1:VAC7, PubMed

YNF8, Complex: FUS1:YNF8, PubMed

Domains

AA: 442-486, PDBID: 1U3O, Subunit A, Seq Identity:28%, SH3 domain

UniProt annotation for FUS1_YEAST » Nuclear fusion protein FUS1
FUNCTION: Required for cell fusion. Negatively regulates Sho1p signaling to ensure efficient cell fusion.

FUNCTION: Interacts with SHO1.

INDUCTION: FUS1 remains essentially unexpressed in vegetative cells, but is strongly induced by incubation of haploid cells with the appropriate mating pheromone.

UniProt features for FUS1_YEAST » Nuclear fusion protein FUS1
CHAIN 1 512 Nuclear fusion protein FUS1.
DOMAIN 436 512 SH3.
REGION 97 512 Hydrophilic.
Amino Acid Sequence for FUS1_YEAST » Nuclear fusion protein FUS1
MVATIMQTTT TVLTTVAAMS TTLASNYISS QASSSTSVTT VTTIATSIRS TPSNLLFSNV AAQPKSSSAS TIGLSIGLPI GIFCFGLLIL LCYFYLKRNS VSISNPPMSA TIPREEEYCR RTNWFSRLFW QSKCEDQNSY SNRDIEKYND TQWTSGDNMS SKIQYKISKP IIPQHILTPK KTVKNPYAWS GKNISLDPKV NEMEEEKVVD AFLYTKPPNI VHIESSMPSY NDLPSQKTVS SKKTALKTSE KWSYESPLSR WFLRGSTYFK DYGLSKTSLK TPTGAPQLKQ MKMLSRISKG YFNESDIMPD ERSPILEYNN TPLDANDSVN NLGNTTPDSQ ITSYRNNNID LITARPHSVI YGTTAQQTLE TNFNDHHDCN KSTEKHELII PTPSKPLKKR KKRRQSKMYQ HLQHLSRSKP LPLTPNSKYN GEASVQLGKT YTVIQDYEPR LTDEIRISLG EKVKILATHT DGWCLVEKCN TQKGSIHVSV DDKRYLNEDR GIVPGDCLQE YD