FTSH4_ARATH » ATP-dependent zinc metalloprotease FTSH 4, mitochondrial

FTSH4_ARATH » ATP-dependent zinc metalloprotease FTSH 4, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
FTSH4_ARATH » ATP-dependent zinc metalloprotease FTSH 4, mitochondrial » AtFTSH4;
Hydrophobic Thickness 29.0 ± 4.8 Å
Tilt Angle 20 ± 16°
ΔGtransfer -16.3 kcal/mol
ΔGfold -7.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 180-201 (177-204)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 263-393, PDBID: 1LV7, Subunit A, Seq Identity:75%, ATPase family associated with various cellular activities (AAA)

AA: 453-654, PDBID: 1IXZ, Subunit A, Seq Identity:48%, Peptidase family M41

UniProt annotation for FTSH4_ARATH » ATP-dependent zinc metalloprotease FTSH 4, mitochondrial
FUNCTION: Probable ATP-dependent zinc metallopeptidase. Involved in the assembly and/or stability of the complex V of the mitochondrial oxidative phosphorylation system.

SUBUNIT: Homooligomer. The complex formed by FTSH4 does not contain FTSH11.

INDUCTION: By high light.

MISCELLANEOUS: In contrast to fungi and metazoa, plant mitochondria have more than one i-AAA-like complexes.

UniProt features for FTSH4_ARATH » ATP-dependent zinc metalloprotease FTSH 4, mitochondrial
TRANSIT 1 28 Mitochondrion (Potential).
CHAIN 29 717 ATP-dependent zinc metalloprotease FTSH 4, mitochondrial.
ACT_SITE 487 487 By similarity.
Amino Acid Sequence for FTSH4_ARATH » ATP-dependent zinc metalloprotease FTSH 4, mitochondrial
MAWRRIITKV SSHERELSSL RSLLVRAYSS FPRVGVTGAV GGGGASLPRT RFQSSYVGSF ARRVRDREEV NEVAHLRELI RRNDPEAVIR MFESQPSLHA NASALSEYIK ALVKVDRLDQ SELVRTLQRG IAGVAREEET FGGLGAFRNV GKPTKDGVLG TASAPIHTIS TERTHFKEQL WSTIRTIGVG FLLISGIGAL IEDRGIGKGL GLHEEVQPSM DSSTKFSDVK GVDEAKAELE EIVHYLRDPK RFTRLGGKLP KGVLLVGPPG TGKTMLARAI AGEAGVPFFS CSGSEFEEMF VGVGARRVRD LFSAAKKCSP CIIFIDEIDA IGGSRNPKDQ QYMKMTLNQM LVELDGFKQN EGIIVVAATN FPESLDKALV RPGRFDRHIV VPNPDVEGRR QILESHMSKV LKAEDVDLMI IARGTPGFSG ADLANLVNVA ALKAAMDGSK DVTMSDLEFA KDRIMMGSER KSAVISDESR KLTAFHEGGH ALVAIHTEGA LPVHKATIVP RGMALGMVSQ LPDKDETSIS RKQMLARLDV CMGGRVAEEL IFGESEVTSG ASSDLEQATK LARAMVTKFG MSKEVGLVAH NYDDNGKSMS TETRLLIESE VKQLLEKAYN NAKTILTVYN KELHALANAL LQHETLSGKQ IKELLTDLNS PLLQKRQEVV TKQSNPVPPS TPSSASSAAA AAAAAAAAAA AAAATAATKG KDMAPVS