FTSH3_ARATH » ATP-dependent zinc metalloprotease FTSH 3, mitochondrial

FTSH3_ARATH » ATP-dependent zinc metalloprotease FTSH 3, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
FTSH3_ARATH » ATP-dependent zinc metalloprotease FTSH 3, mitochondrial » AtFTSH3;
Hydrophobic Thickness 28.2 ± 3.6 Å
Tilt Angle 24 ± 1°
ΔGtransfer -20.7 kcal/mol
ΔGfold -11.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 131-151 (126-151)
Pathways none
PDB none
OPM none
Complexes none
Interactions

FTSHA, Complex: FTSH3:FTSHA

Domains

AA: 134-250, PDBID: 2LNA, Subunit A, Seq Identity:24%, FtsH Extracellular

AA: 358-491, PDBID: 1LV7, Subunit A, Seq Identity:72%, ATPase family associated with various cellular activities (AAA)

AA: 553-756, PDBID: 2QZ4, Subunit A, Seq Identity:49%, Peptidase family M41

UniProt annotation for FTSH3_ARATH » ATP-dependent zinc metalloprotease FTSH 3, mitochondrial
FUNCTION: Probable ATP-dependent zinc metallopeptidase. Involved in the assembly and/or stability of the complexes I and V of the mitochondrial oxidative phosphorylation system.

INDUCTION: By heat and high light.

UniProt features for FTSH3_ARATH » ATP-dependent zinc metalloprotease FTSH 3, mitochondrial
TRANSIT 1 83 Mitochondrion (Potential).
CHAIN 84 809 ATP-dependent zinc metalloprotease FTSH 3, mitochondrial.
ACT_SITE 587 587 By similarity.
Amino Acid Sequence for FTSH3_ARATH » ATP-dependent zinc metalloprotease FTSH 3, mitochondrial
MTMIFFSKLN RSISRSKGFL YGGGVRSAAR LLTSPGLEAA SVNEVEGGLG FIRRHFASLA SRKGLVNNDL IGVFANPRLR RFFSDEAPKK KNYENYFPKD KQEPKSDQKS EHKEGSEKNE NENVGDMFMN RFQNLLIPLL ALAVFFSTFS FGSGEQQQIS FQEFKNKLLE PGLVDHIDVS NKSVAKVYVR STPKDQQTTD VVHGNGNGIP AKRTGGQYKY YFNIGSVDSF EEKLEEAQEA LGVDRHEYVP VTYVSEMVWY QEFMRFAPTL LLLGTLIYGA RRMQGGLGVG GTGGKNGRGI FNIGKATITR ADKHSKNKIY FKDVAGCDEA KQEIMEFVHF LKNPKKYEDL GAKIPKGALL VGPPGTGKTL LAKATAGESG VPFLSISGSD FMEMFVGVGP SRVRHLFQEA RQAAPSIIFI DEIDAIGRAR GRGGLGGNDE RESTLNQLLV EMDGFGTTAG VVVLAGTNRP DILDKALLRP GRFDRQITID KPDIKGRDQI FKIYLKKIKL DHEPSYYSQR LAALTPGFAG ADIANVCNEA ALIAARHEGA TVTMAHFESA IDRVIGGLEK KNRVISKLER RTVAYHESGH AVVGWFLEHA EPLLKVTIVP RGTAALGFAQ YVPNENLLMT KEQLFDMTCM TLGGRAAEQV LIGKISTGAQ NDLEKVTKMT YAQVAVYGFS DKVGLLSFPP RDDGYDFSKP YSNKTGAIID EEVRDWVAKA YERTVELVEE HKVKVAEIAE LLLEKEVLHQ DDLLKILGER PFKSAEVTNY DRFKSGFEET EKDSAATPTV EPVVDDGAPP PFEPQVVPT