FRMD5_HUMAN » FERM domain-containing protein 5

FRMD5_HUMAN » FERM domain-containing protein 5
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
FRMD5_HUMAN » FERM domain-containing protein 5 »
Hydrophobic Thickness 34.4 ± 3.4 Å
Tilt Angle 41 ± 7°
ΔGtransfer -35.3 kcal/mol
ΔGfold -25.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 497-525 (490-525)
Pathways none
PDB none
OPM none
Complexes none
Interactions

CADH1, Complex: CADH1:FRMD5, PubMed

K1467, Complex: FRMD5:K1467

NRCAM, Complex: NRCAM:FRMD5

Domains

AA: 21-84, PDBID: 2HE7, Subunit A, Seq Identity:57%, FERM N-terminal domain

AA: 100-210, PDBID: 1GG3, Subunit C, Seq Identity:53%, FERM central domain

AA: 214-302, PDBID: 1GG3, Subunit C, Seq Identity:27%, FERM C-terminal PH-like domain

AA: 309-352, FERM adjacent (FA)

UniProt features for FRMD5_HUMAN » FERM domain-containing protein 5
CHAIN 1 570 FERM domain-containing protein 5.
DOMAIN 17 298 FERM.
Amino Acid Sequence for FRMD5_HUMAN » FERM domain-containing protein 5
MLSRLMSGSS RSLEREYSCT VRLLDDSEYT CTIQRDAKGQ YLFDLLCHHL NLLEKDYFGI RFVDPDKQRH WLEFTKSVVK QLRSQPPFTM CFRVKFYPAD PAALKEEITR YLVFLQIKRD LYHGRLLCKT SDAALLAAYI LQAEIGDYDS GKHPEGYSSK FQFFPKHSEK LERKIAEIHK TELSGQTPAT SELNFLRKAQ TLETYGVDPH PCKDVSGNAA FLAFTPFGFV VLQGNKRVHF IKWNEVTKLK FEGKTFYLYV SQKEEKKIIL TYFAPTPEAC KHLWKCGIEN QAFYKLEKSS QVRTVSSSNL FFKGSRFRYS GRVAKEVMES SAKIKREPPE IHRAGMVPSR SCPSITHGPR LSSVPRTRRR AVHISIMEGL ESLRDSAHST PVRSTSHGDT FLPHVRSSRT DSNERVAVIA DEAYSPADSV LPTPVAEHSL ELMLLSRQIN GATCSIEEEK ESEASTPTAT EVEALGGELR ALCQGHSGPE EEQVNKFVLS VLRLLLVTMG LLFVLLLLLI ILTESDLDIA FFRDIRQTPE FEQFHYQYFC PLRRWFACKI RSVVSLLIDT