FR1L6_HUMAN » Fer-1-like protein 6

FR1L6_HUMAN » Fer-1-like protein 6
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
FR1L6_HUMAN » Fer-1-like protein 6 »
Hydrophobic Thickness 30.8 ± 4.0 Å
Tilt Angle 33 ± 26°
ΔGtransfer -32.7 kcal/mol
ΔGfold -30.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 1821-1845 (1809-1845)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 83-184, PDBID: 1DQV, Subunit A, Seq Identity:26%, C2 domain

AA: 187-236, FerI (NUC094) domain

AA: 243-357, PDBID: 3NSJ, Subunit A, Seq Identity:26%, C2 domain

AA: 712-784, FerB (NUC096) domain

AA: 826-930, PDBID: 1DQV, Subunit A, Seq Identity:32%, C2 domain

AA: 1004-1098, PDBID: 3L9B, Subunit A, Seq Identity:26%, C2 domain

AA: 1356-1464, PDBID: 4V29, Subunit A, Seq Identity:33%, C2 domain

AA: 1596-1730, PDBID: 1DQV, Subunit A, Seq Identity:26%, C2 domain

AA: 1760-1853, Ferlin C-terminus

UniProt features for FR1L6_HUMAN » Fer-1-like protein 6
CHAIN 1 1857 Fer-1-like protein 6.
DOMAIN 70 160 C2 1.
DOMAIN 230 345 C2 2.
DOMAIN 813 918 C2 3.
DOMAIN 1047 1081 C2 4.
DOMAIN 1343 1441 C2 5.
DOMAIN 1583 1712 C2 6.
Amino Acid Sequence for FR1L6_HUMAN » Fer-1-like protein 6
MFGLKVKKKR NKAEKGLILA NKAAKDSQGD TEALQEEPSH QEGPRGDLVH DDASIFPVPS ASPKRRSKLL TKIHDGEVRS QNYQIAITIT EARQLVGENI DPVVTIEIGD EKKQSTVKEG TNSPFYNEYF VFDFIGPQVH LFDKIIKISV FHHKLIGSVL IGSFKVDLGT VYNQPGHQFC NKWALLTDPG DIRTGTKGYL KCDISVMGKG DVLKTSPKTS DTEEPIEKNL LIPNGFPLER PWARFYVRLY KAEGLPKMNS SIMANVTKAF VGDSKDLVDP FVEVSFAGQM GRTTVQKNCA DPVWHEQVIF KEMFPPLCRR VKIQVWDEGS MNDVALATHF IDLKKISNEQ DGDKGFLPTF GPAWINLYGS PRNHSLMDDY QEMNEGFGEG VSFRGRILVE IAVEILSGRA QESKFSKALK ELKLPSKDKD SKSSKGKDKA DKTEDGKSQQ ASNKTNSTEV EVESFDVPPE IVPEKNEEFL LFGAFFEATM IDRKIGDKPI SFEVSIGNFG NLIDGGSHHG SKKSAESAEE DLLPLLHEGQ GDVAHDVPIP MASTTHPEKP LVTEGNRNYN YLPFEAKKPC VYFISSWGDQ TFRLHWSNML EKMADFLEES IEEVRELIKI SQEAPEEKMK TVLSDFISRS SAFISEAEKK PKMLNQTTLD KKRLTLCWQE LEAMCKEAKG IIQQQKKKLS VDEMIHEAQN FVEKIRFLVD EPQHTIPDVF IWMLSNNRRV AYARIASKDL LYSPVAGQMG KHCGKIKTHF LKPPGKRPAG WSVQAKVDVY LWLGSIKHAS AILDNLPVGY EAEMSSKGAG TNHPPSNLLY QEQHVFQLRA HMYQARGLIA ADSNGLSDPF AKVTFLSHCQ TTKIISQTLS PTWNQMLLFN DLVLHGDVKE LAESPPLVVV ELYDSDAVGK PEYLGATVAA PVVKLADQDY EPPRLCYHPI FCGNLSGGDL LAVFELLQVP PSGLQGLPPV EPPDITQIYP VPANIRPVLS KYRVEVLFWG VREMKKVQLL SVDRPQALIE CGGQGVKSCV IQSYKNNPNF SIQADAFEVE LPENELLHPP LSICVVDWRA FGRSTLVGTY TINYLKQFLC KLREPLAPIT QVDGTQPGHD ISDSLTATES SGAHSSSQDP PADHIYVDVE PPPTVVPDSA QAQPAILVDV PDSSPMLEPE HTPVAQEPPK DGKPKDPRKP SRRSTKRRKR TIADESAENV IDWWSKYYAS LKKAQKAKER NPKGKKGNTE AKPDEVVVDI EDGPKKKKDK MLKKKPKDDG IPNLAILQIY DGDLESEFNN FEDWVKTFEL FRGKSTEDDH GLDGDRVIGK FKGSFCIYKS PQDSSSEDSG QLRIQQGIPP NHPVTVLIRV YIVAAFNLSP ADPDGKSDPY IVIKLGKTEI KDRDKYIPKQ LNPVFGRSFE IQATFPKESL LSILIYDHDM IGTDDLIGET KIDLENRFYS KHRAICGLQS QYEIEGYNAW RDTSKPTEIL TKLCKDNKLD GPYFHPGKIQ IGNQVFSGKT IFTEEDTDET VESYEHLALK VLHSWEDIPE VGCRLVPEHI ETRPLYHKDK PGMEQGRLQM WVDMFPKDMP QPGPPVDISP RRPKGYELRV TIWNTEDVIL EDENIFTGQK SSDIYVKGWL KGLEDDKQET DVHYNSLTGE GNFNWRFLFP FQYLPAEKQM VITKRENIFS LEKMECKTPA VLVLQVWDFE RLSSDDFLGT LEMNLNSFPR AAKSAKACDL AKFENASEET KISIFQQKRV RGWWPFSKSK ELTGKVEAEF HLVTAEEAEK NPVGKARKEP EPLAKPNRPD TSFSWFMSPF KCLYYLIWKN YKKYIIIAFI LIILIIFLVL FIYTLPGAIS RRIVVGS