FR1L4_HUMAN » Fer-1-like protein 4

FR1L4_HUMAN » Fer-1-like protein 4
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
FR1L4_HUMAN » Fer-1-like protein 4 »
Hydrophobic Thickness 32.8 ± 2.8 Å
Tilt Angle 9 ± 6°
ΔGtransfer -31.0 kcal/mol
ΔGfold -24.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 1758-1780 (1751-1780)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 26-131, PDBID: 1V27, Subunit A, Seq Identity:21%, C2 domain

AA: 132-182, FerI (NUC094) domain

AA: 189-302, PDBID: 3NSJ, Subunit A, Seq Identity:31%, C2 domain

AA: 655-725, FerB (NUC096) domain

AA: 761-867, PDBID: 2JQZ, Subunit A, Seq Identity:31%, C2 domain

AA: 1249-1352, PDBID: 1WFJ, Subunit A, Seq Identity:35%, C2 domain

AA: 1492-1626, PDBID: 1UGK, Subunit A, Seq Identity:24%, C2 domain

AA: 1635-1788, Ferlin C-terminus

UniProt features for FR1L4_HUMAN » Fer-1-like protein 4
CHAIN 1 1794 Fer-1-like protein 4.
DOMAIN 13 117 C2 1.
DOMAIN 176 298 C2 2.
DOMAIN 748 853 C2 3.
DOMAIN 1236 1334 C2 4.
DOMAIN 1479 1608 C2 5.
Amino Acid Sequence for FR1L4_HUMAN » Fer-1-like protein 4
MFSPLKSRAR ALAHGDPFQV SRAQDFQVGV TVLEAQKLVG VNINPYVAVQ VGGQRRVTAT QRGTSCPFYN EYFLFEFHDT RLRLQDLLLE ITAFHSQTLP FMATRIGTFR MDLGIILDQP DGQFYQRWVP LHDPRDTRAG TKGFIKVTLS VRARGDLPPP MLPPAPGHCS DIEKNLLLPR GVPAERPWAR LRVRLYRAEG LPALRLGLLG SLVRALHDQR VLVEPYVRVS FLGQEGETSV SAEAAAPEWN EQLSFVELFP PLTRSLRLQL RDDAPLVDAA LATHVPDLRR ISHPGRAAGF NPTFGPAWVP LYGSPPGAGL RDSLQGLNEG VGQGIWFRGR LLLAVSMQVL EGRAEPEPPQ AQQGSTLSRL TRKKKKKARR DQTPKAVPQH LDASPGAEGP EIPRAMEVEV EELLPLPENV LAPCEDFLLF GVLFEATMID PTVASQPISF EISIGRAGRL EEQLGRGSRA GEGTEGAAVE AQPLLGARPE EEKEEEELGT HAQRPEPMDG SGPYFCLPLC HCKPCMHVWS CWEDHTWRLQ SSNCVRKVAE RLDQGLQEVE RLQRKPGPGA CAQLKQALEV LVAGSRQFCH GAERRTMTRP NALDRCRGKL LVHSLNLLAK QGLRLLRGLR RRNVQKKVAL AKKLLAKLRF LAEEPQPPLP DVLVWMLSGQ RRVAWARIPA QDVLFSVVEE ERGRDCGKIQ SLMLTAPGAA PGEVCAKLEL FLRLGLGKQA KACTSELPPD LLPEPSAGLP SSLHRDDFSY FQLRAHLYQA RGVLAADDSG LSDPFARVLI STQCQTTRVL EQTLSPLWDE LLVFEQLIVD GRREHLQEEP PLVIINVFDH NKFGPPVFLG RALAAPRVKL MEDPYQRPEL QFFPLRKGPW AAGELIAAFQ LIELDYSGRL EPSVPSEVEP QDLAPLVEPH SGRLSLPPNV CPVLREFRVE VLFWGLRGLG RVHLLEVEQP QVVLEVAGQG VESEVLASYR ESPNFTELVR HLTVDLPEQP YLQPPLSILV IERRAFGHTV LVGSHIVPHM LRFTFRGHED PPEEEGEMEE TGDMMPKGPQ GQKSLDPFLA EAGISRQLLK PPLKKLPLGG LLNQGPGLEE DIPDPEELDW GSKYYASLQE LQGQHNFDED EMDDPGDSDG VNLISMVGEI QDQGEAEVKG TVSPKKAVAT LKIYNRSLKE EFNHFEDWLN VFPLYRGQGG QDGGGEEEGS GHLVGKFKGS FLIYPESEAV LFSEPQISRG IPQNRPIKLL VRVYVVKATN LAPADPNGKA DPYVVVSAGR ERQDTKERYI PKQLNPIFGE ILELSISLPA ETELTVAVFD HDLVGSDDLI GETHIDLENR FYSHHRANCG LASQYEVDGY NAWRDAFWPS QILAGLCQRC GLPAPEYRAG AVKVGSKVFL TPPETLPPGS SSPTVASGDP EEAQALLVLR RWQEMPGFGI QLVPEHVETR PLYHPHSPGL LQGSLHMWID IFPQDVPAPP PVDIKPRQPI SYELRVVIWN TEDVVLDDEN PLTGEMSSDI YVKSWVKGLE HDKQETDVHF NSLTGEGNFN WRFVFRFDYL PTEREVSVWR RSGPFALEEA EFRQPAVLVL QVWDYDRISA NDFLGSLELQ LPDMVRGARG PELCSVQLAR NGAGPRCNLF RCRRLRGWWP VVKLKEAEDV EREAQEAQAG KKKRKQRRRK GRPEDLEFTD MGGNVYILTG KVEAEFELLT VEEAEKRPVG KGRKQPEPLE KPSRPKTSFN WFVNPLKTFV FFIWRRYWRT LVLLLLVLLT VFLLLVFYTI PGQISQVIFR PLHK