FKB11_HUMAN » FK506-binding protein 11
- Type: 1. Transmembrane bitopic proteins (15 classes)
- Class: 1.13. Enzymes, isomerases (EC 5.) (4 superfamilies)
- Superfamily: 1.13.03. Peptidyl-prolyl cis-trans isomerase, FKBP-type (1 family) PF00254 (Pfam)
- Family: 1.13.03.01. Peptidyl-prolyl cis-trans isomerase, FKBP-type (2 proteins) IPR001179 (InterPro)
- Species: Homo sapiens (2303 proteins)
- Localization: Membrane (682 proteins)
| FKB11_HUMAN » FK506-binding protein 11 » Peptidyl-prolyl cis-trans isomerase;PPIase; Rotamase; 19 kDa FK506-binding protein;FKBP-19; | |
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| Hydrophobic Thickness | 30.0 ± 2.6 Å |
| Tilt Angle | 34 ± 4° |
| ΔGtransfer | -9.5 kcal/mol |
| Links to FKB11_HUMAN | UniProtKB, Pfam, iHOP, STRING, PharmGKB, HGNC, Wikipedia, Interpro |
| Topology | Und |
| Domains | AA: 48-141, PDBID: 2pbc, Subunit A, Seq Identity:49%, FKBP-type peptidyl-prolyl cis-trans isomerase |
| Transmembrane segments |
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| Segments: 156-182 |
| Annotation for FKB11_HUMAN » FK506-binding protein 11 |
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FUNCTION: PPIases accelerate the folding of proteins during protein synthesis. CATALYTIC ACTIVITY: Peptidylproline (omega=180) = peptidylproline (omega=0). SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential). -- Uniprot annotation-- |
| Comments on FKB11_HUMAN » FK506-binding protein 11 |
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SIGNAL 1 27 Potential. CHAIN 28 201 FK506-binding protein 11. DOMAIN 57 144 PPIase FKBP-type. |
