FH8_ARATH » Formin-like protein 8

FH8_ARATH » Formin-like protein 8
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
FH8_ARATH » Formin-like protein 8 » AtFH8; AtFORMIN-1;
Hydrophobic Thickness 37.2 ± 5.0 Å
Tilt Angle 28 ± 1°
ΔGtransfer -26.7 kcal/mol
ΔGfold -17.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 73-102 (69-105)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 297-707, PDBID: 1UX4, Subunit A, Seq Identity:20%, Formin Homology 2 Domain

UniProt annotation for FH8_ARATH » Formin-like protein 8
FUNCTION: Might be involved in the organization and polarity of the actin cytoskeleton. Interacts with the barbed end of actin filaments and nucleates actin-filament polymerization in vitro.

SUBUNIT: Interacts with profilin.

UniProt features for FH8_ARATH » Formin-like protein 8
SIGNAL 1 29 Potential.
CHAIN 30 760 Formin-like protein 8.
DOMAIN 296 732 FH2.
Amino Acid Sequence for FH8_ARATH » Formin-like protein 8
MAAMFNHPWP NLTLIYFFFI VVLPFQSLSQ FDSPQNIETF FPISSLSPVP PPLLPPSSNP SPPSNNSSSS DKKTITKAVL ITAASTLLVA GVFFFCLQRC IIARRRRDRV GPVRVENTLP PYPPPPMTSA AVTTTTLARE GFTRFGGVKG LILDENGLDV LYWRKLQSQR ERSGSFRKQI VTGEEEDEKE VIYYKNKKKT EPVTEIPLLR GRSSTSHSVI HNEDHQPPPQ VKQSEPTPPP PPPSIAVKQS APTPSPPPPI KKGSSPSPPP PPPVKKVGAL SSSASKPPPA PVRGASGGET SKQVKLKPLH WDKVNPDSDH SMVWDKIDRG SFSFDGDLME ALFGYVAVGK KSPEQGDEKN PKSTQIFILD PRKSQNTAIV LKSLGMTREE LVESLIEGND FVPDTLERLA RIAPTKEEQS AILEFDGDTA KLADAETFLF HLLKSVPTAF TRLNAFLFRA NYYPEMAHHS KCLQTLDLAC KELRSRGLFV KLLEAILKAG NRMNAGTARG NAQAFNLTAL LKLSDVKSVD GKTSLLNFVV EEVVRSEGKR CVMNRRSHSL TRSGSSNYNG GNSSLQVMSK EEQEKEYLKL GLPVVGGLSS EFSNVKKAAC VDYETVVATC SALAVRAKDA KTVIGECEDG EGGRFVKTMM TFLDSVEEEV KIAKGEERKV MELVKRTTDY YQAGAVTKGK NPLHLFVIVR DFLAMVDKVC LDIMRNMQRR KVGSPISPSS QRNAVKFPVL PPNFMSDRAW SDSGGSDSDM