FEI2_ARATH » LRR receptor-like serine/threonine-protein kinase FEI 2

FEI2_ARATH » LRR receptor-like serine/threonine-protein kinase FEI 2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
FEI2_ARATH » LRR receptor-like serine/threonine-protein kinase FEI 2 »
Hydrophobic Thickness 35.6 ± 3.2 Å
Tilt Angle 0 ± 0°
ΔGtransfer -44.9 kcal/mol
ΔGfold -15.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 234-262 (234-265)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BET12, Complex: FEI2:BET12

BETL2, Complex: FEI2:BETL2

PAM74, Complex: FEI2:PAM74

UBC32, Complex: FEI2:UBC32

UBC34, Complex: FEI2:UBC34

VAP21, Complex: FEI2:VAP21

WAK3, Complex: FEI2:WAK3

Domains

AA: 29-69, PDBID: 4MN8, Subunit A, Seq Identity:44%, Leucine rich repeat N-terminal domain

AA: 121-181, PDBID: 4J0M, Subunit A, Seq Identity:48%, Leucine rich repeat

AA: 304-571, PDBID: 2A19, Subunit B, Seq Identity:37%, Protein kinase domain

UniProt annotation for FEI2_ARATH » LRR receptor-like serine/threonine-protein kinase FEI 2
FUNCTION: Involved in the signaling pathway that regulates cell wall function, including cellulose biosynthesis, likely via an 1- aminocyclopropane-1-carboxylic acid (ACC)-mediated signal (a precursor of ethylene).

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SUBUNIT: Interacts with the ACC synthases ACS5 and ACS9 but not ACS2, via the kinase domain.

TISSUE SPECIFICITY: Expressed in the root meristem and elongation zone, and in hypocotyls of etiolated seedlings.

MISCELLANEOUS: "Fei" means fat in Chinese.

UniProt features for FEI2_ARATH » LRR receptor-like serine/threonine-protein kinase FEI 2
SIGNAL 1 28 Potential.
CHAIN 29 589 LRR receptor-like serine/threonine- protein kinase FEI 2.
REPEAT 72 96 LRR 1.
REPEAT 97 120 LRR 2.
REPEAT 122 144 LRR 3.
REPEAT 145 168 LRR 4.
REPEAT 170 193 LRR 5.
DOMAIN 304 576 Protein kinase.
ACT_SITE 427 427 Proton acceptor (By similarity).
Amino Acid Sequence for FEI2_ARATH » LRR receptor-like serine/threonine-protein kinase FEI 2
MGICLMKRCC SWFLLISFLS ALTNENEAIS PDGEALLSFR NGVLASDGVI GLWRPEDPDP CNWKGVTCDA KTKRVIALSL TYHKLRGPLP PELGKLDQLR LLMLHNNALY QSIPASLGNC TALEGIYLQN NYITGTIPSE IGNLSGLKNL DLSNNNLNGA IPASLGQLKR LTKFNVSNNF LVGKIPSDGL LARLSRDSFN GNRNLCGKQI DIVCNDSGNS TASGSPTGQG GNNPKRLLIS ASATVGGLLL VALMCFWGCF LYKKLGRVES KSLVIDVGGG ASIVMFHGDL PYASKDIIKK LESLNEEHII GCGGFGTVYK LSMDDGNVFA LKRIVKLNEG FDRFFERELE ILGSIKHRYL VNLRGYCNSP TSKLLLYDYL PGGSLDEALH KRGEQLDWDS RVNIIIGAAK GLAYLHHDCS PRIIHRDIKS SNILLDGNLE ARVSDFGLAK LLEDEESHIT TIVAGTFGYL APEYMQSGRA TEKTDVYSFG VLVLEVLSGK LPTDASFIEK GFNIVGWLNF LISENRAKEI VDLSCEGVER ESLDALLSIA TKCVSSSPDE RPTMHRVVQL LESEVMTPCP SDFYDSSSD