ERJ5_YEAST » ER-localized J domain-containing protein 5

ERJ5_YEAST » ER-localized J domain-containing protein 5
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
ERJ5_YEAST » ER-localized J domain-containing protein 5 »
Hydrophobic Thickness 29.4 ± 2.1 Å
Tilt Angle 7 ± 3°
ΔGtransfer -17.3 kcal/mol
ΔGfold -10.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 129-149 (129-157)
Pathways none
PDB none
OPM none
Complexes none
Interactions

IRE1, Complex: IRE1:ERJ5

OST1, Complex: OST1:ERJ5, PubMed

PMP2, Complex: ERJ5:PMP2, PubMed

Domains

AA: 44-105, PDBID: 2DN9, Subunit A, Seq Identity:40%, DnaJ domain

UniProt annotation for ERJ5_YEAST » ER-localized J domain-containing protein 5
FUNCTION: DnaJ-like chaperone required for the folding capacity of the endoplasmic reticulum.
UniProt features for ERJ5_YEAST » ER-localized J domain-containing protein 5
SIGNAL 1 20
CHAIN 21 295 ER-localized J domain-containing protein 5.
DOMAIN 42 110 J.
Amino Acid Sequence for ERJ5_YEAST » ER-localized J domain-containing protein 5
MNGYWKPALV VLGLVSLSYA FTTIETEIFQ LQNEISTKYG PDMNFYKFLK LPKLQNSSTK EITKNLRKLS KKYHPDKNPK YRKLYERLNL ATQILSNSSN RKIYDYYLQN GFPNYDFHKG GFYFSRMKPK TWFLLAFIWI VVNIGQYIIS IIQYRSQRSR IENFISQCKQ QDDTNGLGVK QLTFKQHEKD EGKSLVVRFS DVYVVEPDGS ETLISPDTLD KPSVKNCLFW RIPASVWNMT FGKSVGSAGK EEIITDSKKY DGNQTKKGNK VKKGSAKKGQ KKMELPNGKV IYSRK