EQTN_HUMAN » Equatorin

EQTN_HUMAN » Equatorin
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
EQTN_HUMAN » Equatorin » Acrosome formation-associated factor;
Hydrophobic Thickness 33.2 ± 4.0 Å
Tilt Angle 39 ± 0°
ΔGtransfer -28.8 kcal/mol
ΔGfold -29.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 175-204 (175-210)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 53-250, Acrosome formation-associated factor

UniProt annotation for EQTN_HUMAN » Equatorin
FUNCTION: Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis.

SUBUNIT: Interacts with SNAP25.

TISSUE SPECIFICITY: Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.

UniProt features for EQTN_HUMAN » Equatorin
SIGNAL 1 14 Potential.
CHAIN 15 294 Equatorin.
Amino Acid Sequence for EQTN_HUMAN » Equatorin
MNFILFIFIP GVFSLKSSTL KPTIEALPNV LPLNEDVNKQ EEKNEDHTPN YAPANEKNGN YYKDIKQYVF TTQNPNGTES EISVRATTDL NFALKNDKTV NATTYEKSTI EEETTTSEPS HKNIQRSTPN VPAFWTMLAK AINGTAVVMD DKDQLFHPIP ESDVNATQGE NQPDLEDLKI KIMLGISLMT LLLFVVLLAF CSATLYKLRH LSYKSCESQY SVNPELATMS YFHPSEGVSD TSFSKSAESS TFLGTTSSDM RRSGTRTSES KIMTDIISIG SDNEMHENDE SVTR