EPGN_HUMAN » Epigen

EPGN_HUMAN » Epigen
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
EPGN_HUMAN » Epigen » Epithelial mitogen;EPG;
Hydrophobic Thickness 30.0 ± 1.8 Å
Tilt Angle 0 ± 2°
ΔGtransfer -44.0 kcal/mol
ΔGfold -19.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 110-133 (107-136)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains none
UniProt annotation for EPGN_HUMAN » Epigen
FUNCTION: Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
UniProt features for EPGN_HUMAN » Epigen
SIGNAL 1 22
CHAIN 23 154 Epigen.
DOMAIN 56 96 EGF-like.
DISULFID 60 73 By similarity.
DISULFID 68 84 By similarity.
DISULFID 86 95 By similarity.
Amino Acid Sequence for EPGN_HUMAN » Epigen
MALGVPISVY LLFNAMTALT EEAAVTVTPP ITAQQGNWTV NKTEADNIEG PIALKFSHLC LEDHNSYCIN GACAFHHELE KAICRCFTGY TGERCEHLTL TSYAVDSYEK YIAIGIGVGL LLSGFLVIFY CYIRKRCLKL KSPYNVCSGE RRPL