EMP24_YEAST » Endosomal protein P24B

EMP24_YEAST » Endosomal protein P24B
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
EMP24_YEAST » Endosomal protein P24B » 24 kDa endomembrane protein;Basic 24 kDa late endocytic intermediate component;
Hydrophobic Thickness 29.2 ± 1.6 Å
Tilt Angle 0 ± 1°
ΔGtransfer -30.4 kcal/mol
ΔGfold -7.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 173-193 (169-198)
Pathways none
PDB none
OPM none
Complexes none
Interactions

ALG1, Complex: ALG1:EMP24, PubMed

ALG5, Complex: ALG5:EMP24, PubMed

CWH41, Complex: EMP24:CWH41

ERG2, Complex: ERG2:EMP24

ERP1, Complex: GRP78:SC61G:PHB2:ERP2:EMP24:ERP1:SCJ1:YEL1, PubMed

ERP1, Complex: ADH1:EMP24:ERP1:ERP4, PubMed

ERP2, Complex: ERP2:EMP24, PubMed

ERP3, Complex: EMP24:ERP3, PubMed

ERP3, Complex: RL4A:HSP71:HSP75:TMEDA:EMP24:ERP3:ERP5, PubMed

ERP4, Complex: RL4B:RSSA1:MPG1:HSP72:HSP75:EMP24:ERP4, PubMed

ERP5, Complex: EMP24:ERP5, PubMed

ERP6, Complex: EMP24:ERP6

FIS1, Complex: EMP24:FIS1

GEM1, Complex: EMP24:GEM1

GSF2, Complex: EMP24:GSF2, PubMed

HKR1, Complex: EMP24:HKR1

HOC1, Complex: EMP24:HOC1

IRE1, Complex: EMP24:IRE1

KRE6, Complex: ODO1:HXKA:ATPA:PRS7:RPN2:RPN1:RPN5:RPN9:RPN12:RPN8:RPN6:HSP77:PRS4:EMP24:KRE6, PubMed

MKAR, Complex: MKAR:EMP24, PubMed

MNL2, Complex: EMP24:MNL2

MSMO, Complex: MSMO:EMP24, PubMed

OST4, Complex: OST4:EMP24, PubMed

PHB2, Complex: EMP24:PHB2, PubMed

PMP2, Complex: EMP24:PMP2, PubMed

ROT1, Complex: EMP24:ROT1

SC61G, Complex: EMP24:SC61G, PubMed

SCS2, Complex: EMP24:SCS2

SEC22, Complex: EMP24:SEC22

SED5, Complex: SED5:EMP24, PubMed

SNL1, Complex: EMP24:SNL1, PubMed

SOP4, Complex: EMP24:SOP4

SRPB, Complex: SRPB:EMP24, PubMed

TLG2, Complex: EMP24:TLG2

TMEDA, Complex: TMEDA:EMP24, PubMed

Domains

AA: 20-198, PDBID: 1M23, Subunit A, Seq Identity:18%, emp24/gp25L/p24 family/GOLD

UniProt annotation for EMP24_YEAST » Endosomal protein P24B
FUNCTION: Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi.

SUBUNIT: Associates with ERV25, ERP1 and ERP2. Interacts also with SAR1, SEC23 and SEC24.

MISCELLANEOUS: Present with 26800 molecules/cell in log phase SD medium.

UniProt features for EMP24_YEAST » Endosomal protein P24B
SIGNAL 1 20
CHAIN 21 203 Endosomal protein P24B.
DOMAIN 30 118 GOLD.
Amino Acid Sequence for EMP24_YEAST » Endosomal protein P24B
MASFATKFVI ACFLFFSASA HNVLLPAYGR RCFFEDLSKG DELSISFQFG DRNPQSSSQL TGDFIIYGPE RHEVLKTVRD TSHGEITLSA PYKGHFQYCF LNENTGIETK DVTFNIHGVV YVDLDDPNTN TLDSAVRKLS KLTREVKDEQ SYIVIRERTH RNTAESTNDR VKWWSIFQLG VVIANSLFQI YYLRRFFEVT SLV