EMC7_HUMAN » ER membrane protein complex subunit 7

EMC7_HUMAN » ER membrane protein complex subunit 7
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
EMC7_HUMAN » ER membrane protein complex subunit 7 »
Hydrophobic Thickness 31.6 ± 2.6 Å
Tilt Angle 28 ± 12°
ΔGtransfer -24.4 kcal/mol
ΔGfold -12.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 164-185 (164-186)
Pathways none
PDB 1b0g (C/F=4-12), 1lp9 (C/J=4-12), 2j8u (C/J=4-12), 2jcc (C/J=4-12), 2uwe (C/J=4-12)
OPM none
Complexes

EMC7:TCA:1A02:B2MG_HUMAN

TVB5:EMC7:TCA:1A02:B2MG_HUMAN

EMC7:1A02:B2MG_HUMAN

Interactions

1A02, Complex: EMC7:1A02:B2MG, PDBID: 1B0G

EMC10, Complex: EMC7:EMC10

EMC1, Complex: EMC7:EMC1

MMGT1, Complex: EMC7:MMGT1

TCA, Complex: TVB5:EMC7:TCA:1A02:B2MG, PDBID: 1LP9

Domains

AA: 56-168, Protein of unknown function (DUF2012)

UniProt annotation for EMC7_HUMAN » ER membrane protein complex subunit 7
SUBUNIT: Component of the ER membrane protein complex (EMC).
UniProt features for EMC7_HUMAN » ER membrane protein complex subunit 7
SIGNAL 1 23 Potential.
CHAIN 24 242 ER membrane protein complex subunit 7.
Amino Acid Sequence for EMC7_HUMAN » ER membrane protein complex subunit 7
MAAALWGFFP VLLLLLLSGD VQSSEVPGAA AEGSGGSGVG IGDRFKIEGR AVVPGVKPQD WISAARVLVD GEEHVGFLKT DGSFVVHDIP SGSYVVEVVS PAYRFDPVRV DITSKGKMRA RYVNYIKTSE VVRLPYPLQM KSSGPPSYFI KRESWGWTDF LMNPMVMMMV LPLLIFVLLP KVVNTSDPDM RREMEQSMNM LNSNHELPDV SEFMTRLFSS KSSGKSSSGS SKTGKSGAGK RR