EMC1_HUMAN » ER membrane protein complex subunit 1

EMC1_HUMAN » ER membrane protein complex subunit 1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
EMC1_HUMAN » ER membrane protein complex subunit 1 »
Hydrophobic Thickness 27.2 ± 2.2 Å
Tilt Angle 0 ± 0°
ΔGtransfer -36.7 kcal/mol
ΔGfold -15.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 962-982 (959-983)
Pathways none
PDB none
OPM none
Complexes none
Interactions

CALX, Complex: CALX:EMC1

EMC7, Complex: EMC7:EMC1

MMGT1, Complex: MMGT1:EMC1

Domains

AA: 21-252, PDBID: 4MH1, Subunit A, Seq Identity:35%, PQQ-like domain

AA: 787-992, Protein of unknown function (DUF1620)

UniProt annotation for EMC1_HUMAN » ER membrane protein complex subunit 1
SUBUNIT: Component of the ER membrane protein complex (EMC).
UniProt features for EMC1_HUMAN » ER membrane protein complex subunit 1
SIGNAL 1 21 Potential.
CHAIN 22 993 ER membrane protein complex subunit 1.
Amino Acid Sequence for EMC1_HUMAN » ER membrane protein complex subunit 1
MAAEWASRFW LWATLLIPAA AVYEDQVGKF DWRQQYVGKV KFASLEFSPG SKKLVVATEK NVIAALNSRT GEILWRHVDK GTAEGAVDAM LLHGQDVITV SNGGRIMRSW ETNIGGLNWE ITLDSGSFQA LGLVGLQESV RYIAVLKKTT LALHHLSSGH LKWVEHLPES DSIHYQMVYS YGSGVVWALG VVPFSHVNIV KFNVEDGEIV QQVRVSTPWL QHLSGACGVV DEAVLVCPDP SSRSLQTLAL ETEWELRQIP LQSLDLEFGS GFQPRVLPTQ PNPVDASRAQ FFLHLSPSHY ALLQYHYGTL SLLKNFPQTA LVSFATTGEK TVAAVMACRN EVQKSSSSED GSMGSFSEKS SSKDSLACFN QTYTINLYLV ETGRRLLDTT ITFSLEQSGT RPERLYIQVF LKKDDSVGYR ALVQTEDHLL LFLQQLAGKV VLWSREESLA EVVCLEMVDL PLTGAQAELE GEFGKKADGL LGMFLKRLSS QLILLQAWTS HLWKMFYDAR KPRSQIKNEI NIDTLARDEF NLQKMMVMVT ASGKLFGIES SSGTILWKQY LPNVKPDSSF KLMVQRTTAH FPHPPQCTLL VKDKESGMSS LYVFNPIFGK WSQVAPPVLK RPILQSLLLP VMDQDYAKVL LLIDDEYKVT AFPATRNVLR QLHELAPSIF FYLVDAEQGR LCGYRLRKDL TTELSWELTI PPEVQRIVKV KGKRSSEHVH SQGRVMGDRS VLYKSLNPNL LAVVTESTDA HHERTFIGIF LIDGVTGRII HSSVQKKAKG PVHIVHSENW VVYQYWNTKA RRNEFTVLEL YEGTEQYNAT AFSSLDRPQL PQVLQQSYIF PSSISAMEAT ITERGITSRH LLIGLPSGAI LSLPKALLDP RRPEIPTEQS REENLIPYSP DVQIHAERFI NYNQTVSRMR GIYTAPSGLE STCLVVAYGL DIYQTRVYPS KQFDVLKDDY DYVLISSVLF GLVFATMITK RLAQVKLLNR AWR