EAR1_YEAST » Protein EAR1

EAR1_YEAST » Protein EAR1
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Topology in Endosome membrane
Topologyendosome lumenal side
cytoplasmic side
EAR1_YEAST » Protein EAR1 » Endosomal adapter of RSP5;
Hydrophobic Thickness 31.6 ± 2.6 Å
Tilt Angle 43 ± 0°
ΔGtransfer -31.4 kcal/mol
ΔGfold -23.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 44-68 (44-73)
Pathways none
PDB none
OPM none
Complexes none
Interactions

MTL1, Complex: EAR1:MTL1

Domains

AA: 237-373, PDBID: 2YYO, Subunit A, Seq Identity:22%, SPRY domain

UniProt annotation for EAR1_YEAST » Protein EAR1
FUNCTION: Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity).

MISCELLANEOUS: Present with 656 molecules/cell in log phase SD medium.

UniProt features for EAR1_YEAST » Protein EAR1
CHAIN 1 550 Protein EAR1.
DOMAIN 172 375 B30.2/SPRY.
Amino Acid Sequence for EAR1_YEAST » Protein EAR1
MSFKFLIESL LLGSISGQIR CGRSSVIPRG DVSYGGDDTD ELNMDIMLFA FGTLIVVYIV ICIVYFFTKQ IATRLITAYY NEHGPGQRIS LFSDYDENNA HVHSRRLMEN MSLRWPNNLD DADEVRDKLA QLSPEEQFYY KQGEEYIKQN PPFLLNQGLL QQSEDSNPDT TREDPIMNEQ TRQYIQEEGA YAWEFSPNPD MPNHTVIVEN KTEVSFLNYN YDASISTNLP IPCINKVYYC EFKIFETDGP LNSDENVSKG VISFGLSTQP YPYFRLPGRH HHSIAYDSNG ARRFNDSFKL NEQLRTLFPQ CEKGDIVGIG YRSRSGTVFF TRNGKKLNEK SVGGHIRGWK FQYLYPIIGS NVPCQIHVNF GTYGFVYIEA NVKKWGYAKS NGIKLPPPSY EDYGKDTLLE SGGEDNDFDE DFSDGDSDNI AAGSTTNLND DIIIRNGEIL PPPPGFEFTM SPPTGKKIIN EEINLDSLPM LPPSYSDDEH HSKNDKSAIS GRIIGTSRNL ITDEASFDSV DNDNEDENDH ERDPEQFSEF DDYESRMHGI