DRKC_DICDI » Probable serine/threonine-protein kinase drkC

DRKC_DICDI » Probable serine/threonine-protein kinase drkC
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
DRKC_DICDI » Probable serine/threonine-protein kinase drkC » Receptor-like kinase 3;Receptor-like kinase C;Vesicle-associated receptor tyrosine kinase-like protein 3;
Hydrophobic Thickness 34.8 ± 1.4 Å
Tilt Angle 0 ± 2°
ΔGtransfer -49.3 kcal/mol
ΔGfold -25.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 419-447 (416-451)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 313-402, PDBID: 3MLP, Subunit E, Seq Identity:22%, IPT/TIG domain

AA: 491-746, PDBID: 3BKB, Subunit A, Seq Identity:38%, Protein tyrosine kinase

UniProt annotation for DRKC_DICDI » Probable serine/threonine-protein kinase drkC
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
UniProt features for DRKC_DICDI » Probable serine/threonine-protein kinase drkC
SIGNAL 1 31 Potential.
CHAIN 32 749 Probable serine/threonine-protein kinase drkC.
DOMAIN 491 749 Protein kinase.
ACT_SITE 615 615 Proton acceptor (By similarity).
Amino Acid Sequence for DRKC_DICDI » Probable serine/threonine-protein kinase drkC
MIIINKYIRM NKIAILFSFF ILICCTGYSI SYKINGINEN KVLSLSSSPS PSSSSSSSQI LEKGKEEIKK IKKTNKNKLL YNVAIVDLEP KLEIEQELLT RNNKKKMEMK EEMDIAMMMM KAADRTDQVS TSSSSSSFSE ENKKSSSDDS APAIQSNLTF SGYMTGGEQV CDPKSCNSPS VFTQNYLCNT SSAWANGYVF HDPVPPTGLF VVHKIVVTFT GMFNVIPPTS MVFSLVNGEE NAGIFFISKS SPSQCPNCQI SFSPRTLPDV DPNGLASYRY GSNNSIIFNL FETDVACIGK VTANIFYGPV AFKVNSVVPN TAPSTGGETV YFIGEQFYQS SQIQCKFGTV ISTGTYINST CASCVVPPML QSNSTTPSDY NVTIQLSEDG GSSFCLNTTF FIYTAASIPF VKPTSPNYQK IIYIVVGVGI AVLLIIAVGI YFIIRLRIKN KRLNGSKHAL PIGINDDERS PLLKTDYKTL FEIKPIDISE IVVQNRIGRG SCAEVFTGTW RGIIVAIKKA KLLNEDDEDF LNELAQEATI MSQLRHPNIC QFLGTCNNPP EILIVMEYMP LGSLYRILHD PSISLDWPRM KSMALDIAKG MNYLHCCDPI VIHRDLKSHN LLVDEHYRVK ISDFGLSTRF KKHLDKKTAM TPVGTPCWTA PEVLRNDPYT EKADVFSFAI VLWEIVTRED PYQGMPTFQI VISVGQHKLR PIVPPQVSAP FTRLITECWS EDPQQRPSFQ EIVKRLEAM