DRKA_DICDI » Probable serine/threonine-protein kinase drkA

DRKA_DICDI » Probable serine/threonine-protein kinase drkA
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
DRKA_DICDI » Probable serine/threonine-protein kinase drkA » Receptor-like kinase 1;Receptor-like kinase A;Vesicle-associated receptor tyrosine kinase-like protein 1;
Hydrophobic Thickness 33.6 ± 6.2 Å
Tilt Angle 37 ± 5°
ΔGtransfer -24.0 kcal/mol
ΔGfold -14.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 316-343 (316-350)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 374-624, PDBID: 1UWH, Subunit B, Seq Identity:45%, Protein tyrosine kinase

UniProt annotation for DRKA_DICDI » Probable serine/threonine-protein kinase drkA
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
UniProt features for DRKA_DICDI » Probable serine/threonine-protein kinase drkA
SIGNAL 1 23 Potential.
CHAIN 24 642 Probable serine/threonine-protein kinase drkA.
DOMAIN 374 627 Protein kinase.
ACT_SITE 497 497 Proton acceptor (By similarity).
Amino Acid Sequence for DRKA_DICDI » Probable serine/threonine-protein kinase drkA
MKKLPFLIII IYIFLILISI SSSIDYNYNN DIDNNNNNII NRNKNKNKNN LYNNKVIIKN DDNDDEINNK FKIRLDDNED QDIYNEYHFL SKVHNRLAFN IFGSSSENSG SGSNSNSNSK NTDSSTGPTP SPISINGTLN STATVYWSGG KSSCKSVNCT EEGFSTGDSY ACSYEITPTY QRGQWEKGVK YFKDPLPKSI LTSQVVGVSF VINGVVGCTP LKQELTTIEF LIQDVQVGQT ISTNRSDDCS CGICYKDYEI LPQSYDLLGY NKSGLNKVQL LLLDNSICAT SLDIIFYYHP STIPPTPTPT PSKPTISLLK KYLIIGFSIV GGLLIIGGCF LLIRNRYRSS GYYKPDKNDY TQIKDGKDID IHQIKIGVRI GKGNYGEVYL GTWRGSQVAV KKLPAHNINE NILKEFHREI NLMKNLRHPN VIQFLGSCLI PPDICICTEY MPRGSLYSIL HDQALQLQWS LLIKMMIDAA KGVIYLHNST PVILHRDLKS HNLLVDENWK VKVADFGLST IEQQGATMTA CGTPCWTSPE VLRSQRYTEK ADVYSFGIIL WECATRQDPY FGIPPFQVIF AVGREGMRPP VPQNGPPKYI QLLIDCLNEN PSHRPTMEQC LERLESIDSS GYSDLQYVRQ QL