DNJC1_HUMAN » DnaJ homolog subfamily C member 1
3D view in Chime, Jmol or Webmol
Download Coordinates
Topology in Endoplasmic reticulum membrane
Download Coordinates
Topology in Endoplasmic reticulum membrane
 | lumenal side |
| cytoplasmic side |
- Type: 1. Transmembrane bitopic proteins (15 classes)
- Class: 1.04. Protein biogenesis and transport (41 superfamilies)
- Superfamily: 1.04.20. DnaJ-related (3 families) PF00026 (Pfam)
- Family: 1.04.20.02. DnaJ homolog family C (6 proteins) IPR001623 (InterPro)
- Species: Homo sapiens (2303 proteins)
- Localization: Endoplasmic reticulum membrane (209 proteins)
| DNJC1_HUMAN » DnaJ homolog subfamily C member 1 » DnaJ protein homolog MTJ1; | |
|---|---|
| Hydrophobic Thickness | 29.6 ± 2.6 Å |
| Tilt Angle | 33 ± 8° |
| ΔGtransfer | -15.0 kcal/mol |
| Links to DNJC1_HUMAN | UniProtKB, Pfam, iHOP, STRING, PharmGKB, HGNC, Wikipedia, Interpro |
| Topology | Out |
| Domains | AA: 65-126, PDBID: 2dmx, Subunit A, Seq Identity:53%, DnaJ domain AA: 327-385, PDBID: 2cqq, Subunit A, Seq Identity:100%, AA: 494-543, PDBID: 2cqr, Subunit A, Seq Identity:100%, Myb-like DNA-binding domain |
| Transmembrane segments |
|---|
| Segments: 151-178 |
| Uniprot annotation for DNJC1_HUMAN » DnaJ homolog subfamily C member 1 |
|---|
|
FUNCTION: May modulate protein synthesis (By similarity). SUBUNIT: Interacts (via J domain) with HSPA5. Interacts (via cytosolic domain) with ribosomes (By similarity). Interacts (via SANT domain) with SERPINA3. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type I membrane protein (By similarity). Nucleus membrane; Single- pass type I membrane protein. Microsome membrane; Single-pass type I membrane protein (By similarity). -- Uniprot annotation-- |
| Uniprot features for DNJC1_HUMAN » DnaJ homolog subfamily C member 1 |
|---|
|
SIGNAL 1 47 Potential. CHAIN 48 554 DnaJ homolog subfamily C member 1. DOMAIN 65 129 J. DOMAIN 325 379 SANT 1. DOMAIN 492 547 SANT 2. |
