DJB12_HUMAN » DnaJ homolog subfamily B member 12

DJB12_HUMAN » DnaJ homolog subfamily B member 12
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
DJB12_HUMAN » DnaJ homolog subfamily B member 12 »
Hydrophobic Thickness 31.6 ± 2.6 Å
Tilt Angle 1 ± 1°
ΔGtransfer -22.1 kcal/mol
ΔGfold -13.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 246-266 (246-269)
Pathways

Protein processing in endoplasmic reticulum (KEGG)

PDB 2ctp (110-174)
OPM none
Complexes none
Interactions

EGFR, Complex: DJB12:EGFR

NEP, Complex: NEP:DJB12, PubMed

TNR1A, Complex: TNR1A:DJB12, PubMed

Domains

AA: 110-171, PDBID: 2CTP, Subunit A, Seq Identity:100%, DnaJ domain

AA: 262-368, Domain of unknown function (DUF1977)

UniProt features for DJB12_HUMAN » DnaJ homolog subfamily B member 12
CHAIN 1 375 DnaJ homolog subfamily B member 12.
DOMAIN 112 176 J.
Amino Acid Sequence for DJB12_HUMAN » DnaJ homolog subfamily B member 12
MESNKDEAER CISIALKAIQ SNQPDRALRF LEKAQRLYPT PRVRALIESL NQKPQTAGDQ PPPTDTTHAT HRKAGGTDAP SANGEAGGES TKGYTAEQVA AVKRVKQCKD YYEILGVSRG ASDEDLKKAY RRLALKFHPD KNHAPGATEA FKAIGTAYAV LSNPEKRKQY DQFGDDKSQA ARHGHGHGDF HRGFEADISP EDLFNMFFGG GFPSSNVHVY SNGRMRYTYQ QRQDRRDNQG DGGLGVFVQL MPILILILVS ALSQLMVSSP PYSLSPRPSV GHIHRRVTDH LGVVYYVGDT FSEEYTGSSL KTVERNVEDD YIANLRNNCW KEKQQKEGLL YRARYFGDTD MYHRAQKMGT PSCSRLSEVQ ASLHG