CSF1_YEAST » Protein CSF1

CSF1_YEAST » Protein CSF1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CSF1_YEAST » Protein CSF1 » Cold sensitive for fermentation protein 1;
Hydrophobic Thickness 34.0 ± 2.0 Å
Tilt Angle 30 ± 7°
ΔGtransfer -25.7 kcal/mol
ΔGfold -12.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 20-45 (19-47)
Pathways

Cytokine-cytokine receptor interaction (KEGG)

Hematopoietic cell lineage (KEGG)

Osteoclast differentiation (KEGG)

PI3K-Akt signaling pathway (KEGG)

Rheumatoid arthritis (KEGG)

TNF signaling pathway (KEGG)

PDB none
OPM none
Complexes none
Interactions

ALG5, Complex: CSF1:ALG5

ANP1, Complex: CSF1:ANP1

BIG1, Complex: CSF1:BIG1

CALX, Complex: CALX:CSF1

CP51, Complex: CSF1:CP51

CWH41, Complex: CSF1:CWH41

ERG5, Complex: CSF1:ERG5

FZO1, Complex: FZO1:CSF1

HOC1, Complex: CSF1:HOC1

IRE1, Complex: CSF1:IRE1

KEX2, Complex: CSF1:KEX2

MID2, Complex: CSF1:MID2

MKAR, Complex: CSF1:MKAR

MMM1, Complex: CSF1:MMM1

MNN10, Complex: MNN10:CSF1

MNN11, Complex: MNN11:CSF1

MTC4, Complex: CSF1:MTC4

MTC6, Complex: CSF1:MTC6

OST1, Complex: CSF1:OST1

OSTB, Complex: CSF1:OSTB

PHB2, Complex: PHB2:CSF1

PSD1, Complex: PSD1:CSF1

SEC22, Complex: SEC22:CSF1

SEC66, Complex: CSF1:SEC66

SSO2, Complex: SSO2:CSF1

TLG2, Complex: TLG2:CSF1

TRE1, Complex: CSF1:TRE1

VOA1, Complex: CSF1:VOA1

Domains none
UniProt annotation for CSF1_YEAST » Protein CSF1
FUNCTION: Required for the glucose and other nutrients uptake at low temperature.
UniProt features for CSF1_YEAST » Protein CSF1
CHAIN 1 2958 Protein CSF1.
Amino Acid Sequence for CSF1_YEAST » Protein CSF1
MEAISQLRGV PLTHQKDFSW VFLVDWILTV VVCLTMIFYM GRIYAYLVSF ILEWLLWKRA KIKINVETLR VSLLGGRIHF KNLSVIHKDY TISVLEGSLT WKYWLLNCRK AELIENNKSS SGKKAKLPCK ISVECEGLEI FIYNRTVAYD NVINLLSKDE RDKFEKYLNE HSFPEPFSDG SSADKLDEDL SESAYTTNSD ASIVNDRDYQ ETDIGKHPKL LMFLPIELKF SRGSLLLGNK FTPSVMILSY ESGKGIIDVL PPKERLDLYR NKTQMEFKNF EISIKQNIGY DDAIGLKFKI DRGKVSKLWK TFVRVFQIVT KPVVPKKTKK SAGTSDDNFY HKWKGLSLYK ASAGDAKASD LDDVEFDLTN HEYAKFTSIL KCPKVTIAYD VDVPGVVPHG AHPTIPDIDG PDVGNNGAPP DFALDVQIHG GSICYGPWAQ RQVSHLQRVL SPVVSRTAKP IKKLPPGSRR IYTLFRMNIS IMEDTTWRIP TRESSKDPEF LKHYKETNEE YRPFGWMDLR FCKDTYANFN ISVCPTVQGF QNNFHVHFLE TEIRSSVNHD ILLKSKVFDI DGDIGYPLGW NSKAIWIINM KSEQLEAFLL REHITLVADT LSDFSAGDPT PYELFRPFVY KVNWEMEGYS IYLNVNDHNI VNNPLDFNEN CYLSLHGDKL SIDVTVPRES ILGTYTDMSY EISTPMFRMM LNTPPWNTLN EFMKHKEVGR AYDFTIKGSY LLYSELDIDN VDTLVIECNS KSTVLHCYGF VMRYLTNVKM NYFGEFFNFV TSEEYTGVLG AREVGDVTTK SSVADLASTV DSGYQNSSLK NESEDKGPMK RSDLKRTTNE TDIWFTFSVW DGALILPETI YSFDPCIALH FAELVVDFRS CNYYMDIMAV LNGTSIKRHV SKQINEVFDF IRRNNGADEQ EHGLLSDLTI HGHRMYGLPP TEPTYFCQWD INLGDLCIDS DIEFIKGFFN SFYKIGFGYN DLENILLYDT ETINDMTSLT VHVEKIRIGL KDPVMKSQSV ISAESILFTL IDFENEKYSQ RIDVKIPKLT ISLNCVMGDG VDTSFLKFET KLRFTNFEQY KDIDKKRSEQ RRYITIHDSP YHRCPFLLPL FYQDSDTYQN LYGAIAPSSS IPTLPLPTLP DTIDYIIEDI VGEYATLLET TNPFKNIFAE TPSTMEPSRA SFSEDDNDEE ADPSSFKPVA FTEDRNHERD NYVVDVSYIL LDVDPLLFIF AKSLLEQLYS ENMVQVLDDI EIGIVKRLSN LQEGITSISN IDIHIAYLNL IWQETGEEGF ELYLDRIDYQ MSEKSLEKNR TNKLLEVAAL AKVKTVRVTV NQKKNPDLSE DRPPALSLGI EGFEVWSSTE DRQVNSLNLT SSDITIDESQ MEWLFEYCSD QGNLIQEVCT SFNSIQNTRS NSKTELISKL TAASEYYQIS HDPYVITKPA FIMRLSKGHV RENRSWKIIT RLRHILTYLP DDWQSNIDEV LKEKKYTSAK DAKNIFMSVF STWRNWEFSD VARSYIYGKL FTAENEKHKQ NLIKKLLKCT MGSFYLTVYG EGYEVEHNFV VADANLVVDL TPPVTSLPSN REETIEITGR VGSVKGKFSD RLLKLQDLIP LIAAVGEDDK SDPKKELSKQ FKMNTVLLVD KSELQLVMDQ TKLMSRTVGG RVSLLWENLK DSTSQAGSLV IFSQKSEVWL KHTSVILGEA QLRDFSVLAT TEAWSHKPTI LINNQCADLH FRAMSSTEQL VTAITEIRES LMMIKERIKF KPKSKKKSQF VDQKINTVLS CYFSNVSSEV MPLSPFYIRH EAKQLDIYFN KFGSNEILLS IWDTDFFMTS HQTKEQYLRF SFGDIEIKGG ISREGYSLIN VDISISMIKL TFSEPRRIVN SFLQDEKLAS QGINLLYSLK PLFFSSNLPK KEKQAPSIMI NWTLDTSITY FGVLVPVAST YFVFELHMLL LSLTNTNNGM LPEETKVTGQ FSIENILFLI KERSLPIGLS KLLDFSIKVS TLQRTVDTEQ SFQVESSHFR VCLSPDSLLR LMWGAHKLLD LSHYYSRRHA PNIWNTKMFT GKSDKSKEMP INFRSIHILS YKFCIGWIFQ YGAGSNPGLM LGYNRLFSAY EKDFGKFTVV DAFFSVANGN TSSTFFSEGN EKDKYNRSFL PNMQISYWFK RCGELKDWFF RFHGEALDVN FVPSFMDVIE STLQSMRAFQ ELKKNILDVS ESLRAENDNS YASTSVESAS SSLAPFLDNI RSVNSNFKYD GGVFRVYTYE DIETKSEPSF EIKSPVVTIN CTYKHDEDKV KPHKFRTLIT VDPTHNTLYA GCAPLLMEFS ESLQKMIKKH STDEKPNFTK PSSQNVDYKR LLDQFDVAVK LTSAKQQLSL SCEPKAKVQA DVGFESFLFS MATNEFDSEQ PLEFSLTLEH TKASIKHIFS REVSTSFEVG FMDLTLLFTH PDVISMYGTG LVSDLSVFFN VKQLQNLYLF LDIWRFSSIL HTRPVQRTVN KEIEMSSLTS TNYADAGTEI PWCFTLIFTN VSGDVDLGPS LGMISLRTQR TWLATDHYNE KRQLLHAFTD GISLTSEGRL SGLFEVANAS WLSEVKWPPE KSKNTHPLVS TSLNIDDIAV KAAFDYHMFL IGTISNIHFH LHNEKDAKGV LPDLLQVSFS SDEIILSSTA LVVANILDIY NTIVRMRQDN KISYMETLRD SNPGESRQPI LYKDILRSLK LLRTDLSVNI SSSKVQISPI SLFDVEVLVI RIDKVSIRSE THSGKKLKTD LQLQVLDVSA ALSTSKEELD EEVGASIAID DYMHYASKIV GGTIIDIPKL AVHMTTLQEE KTNNLEYLFA CSFSDKISVR WNLGPVDFIK EMWTTHVKAL AVRRSQVANI SFGQTEEELE ESIKKEEAAS KFNYIALEEP QIEVPQIRDL GDATPPMEWF GVNRKKFPKF THQTAVIPVQ KLVYLAEKQY VKILDDTH