CRK6_ARATH » Cysteine-rich receptor-like protein kinase 6

CRK6_ARATH » Cysteine-rich receptor-like protein kinase 6
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CRK6_ARATH » Cysteine-rich receptor-like protein kinase 6 » Cysteine-rich RLK6; Receptor-like protein kinase 5;
Hydrophobic Thickness 35.6 ± 3.2 Å
Tilt Angle 8 ± 5°
ΔGtransfer -30.2 kcal/mol
ΔGfold -27.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 287-311 (287-316)
Pathways none
PDB none
OPM none
Complexes none
Interactions

P2C70, Complex: CRK6:P2C70, PubMed

Domains

AA: 33-130, Salt stress response/antifungal

AA: 147-243, Salt stress response/antifungal

AA: 247-340, Proline-rich membrane anchor 1

AA: 351-622, PDBID: 3TL8, Subunit A, Seq Identity:50%, Protein kinase domain

UniProt annotation for CRK6_ARATH » Cysteine-rich receptor-like protein kinase 6
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

INDUCTION: By salicylic acid (SA) or by a bacterial pathogen infection. May be regulated by WRKY DNA-binding proteins at the transcriptional level.

UniProt features for CRK6_ARATH » Cysteine-rich receptor-like protein kinase 6
SIGNAL 1 24 Potential.
CHAIN 25 674 Cysteine-rich receptor-like protein kinase 6.
DOMAIN 28 132 Gnk2-homologous 1.
DOMAIN 139 245 Gnk2-homologous 2.
DOMAIN 351 637 Protein kinase.
ACT_SITE 476 476 Proton acceptor (By similarity).
Amino Acid Sequence for CRK6_ARATH » Cysteine-rich receptor-like protein kinase 6
MSSLISFNFL FLFSFLTSSF TASAQDPFYL NHYCPNTTTY SSNSTYSTNL RTLLSSLSSR NASYSTGFQN ATAGKAPDRV TGLFLCRGDV SPEVCRNCVA FSVNQTLNLC PKVREAVFYY EQCILRYSHK NILSTAITNE GEFILSNTNT ISPNQKQIDG FTSFVSSTMS EAAGKAANSS RKLYTVNTEL TAYQNLYGLL QCTPDLTRAD CLSCLQSSIN GMALSRIGAR LYWPSCTARY ELYPFYNESA IETPPLPPPP PPPPPRESLV STPPISSSSL PGKSGNSTVL VVAVVVLAVL LFIALVGYCF LAKKKKKTFD TASASEVGDD MATADSLQLD YRTIQTATND FAESNKIGRG GFGEVYKGTF SNGKEVAVKR LSKNSRQGEA EFKTEVVVVA KLQHRNLVRL LGFSLQGEER ILVYEYMPNK SLDCLLFDPT KQIQLDWMQR YNIIGGIARG ILYLHQDSRL TIIHRDLKAS NILLDADINP KIADFGMARI FGLDQTQDNT SRIVGTYGYM APEYAMHGQF SMKSDVYSFG VLVLEIISGR KNSSFGESDG AQDLLTHAWR LWTNKKALDL VDPLIAENCQ NSEVVRCIHI GLLCVQEDPA KRPAISTVFM MLTSNTVTLP VPRQPGFFIQ CRAVKDPLDS DQSTTTKSFP ASIDDESITD LYPR